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科学家 Patrick O Brown(基因组学)

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Patrick O Brown
8~9Pt2O8d-X ^"Y0Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
e)HF,m#^ O9r g0is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网Jhh;Qq*qG qN*S0_
in pattern of gene expression. The output is displayed graphically, conveying the...
bx*CN fO i(XWv0Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网*M#mTS{S
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com分析测试百科网F5R}"~J
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
8{2kW,aajo0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
}8a+y'U*c1hG-n9K0prolonged survival, whereas the remainder succumb to the disease. We proposed that...
-KnfY7dwS0Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com
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Human breast tumours are diverse in their natural history and in their responsiveness to treatments
wU7K,|qwi01 . Variation in transcriptional programs accounts for much of the biological diversity of human
C_AP W6J O)v0cells and tumours. In each cell, signal transduction and regulatory systems transduce...
r,n:g-AWr^|1U0Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org
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DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
;Z)F_7V7YMi1Z0carry out a comprehensive investigation of the temporal program of gene expression accompanying
1Jm3P|adxiV@7^0the metabolic shift from fermentation to respiration. The expression profiles observed for...分析测试百科网$s,T g^rtK'] T
Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol分析测试百科网 D/F0uz/U x(]Mg,h'F
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
3kWFD9M ^0during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
y$aW2[B P"jo6y0regulated have been identified using traditional methods, and it was estimated that some...分析测试百科网a2]#JEgp#E&F0i
Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
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The purpose of this study was to classify breast carcinomas based on variations in gene expression
#he,r A5K;h{"k0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical分析测试百科网(f%}K z#|(I5Fr?s
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...
gw~ z?yo@0Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol
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We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding分析测试百科网8s:m|9vB(OM
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.分析测试百科网yN'd*g%w6S N,Z
levels over time for almost every yeast gene, as cells responded to temperature shocks,...分析测试百科网wrpqR
Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网o9YUL$q*QY g/_
for biologists to imagine that the genes that had been discovered via mutations, selections and分析测试百科网j;h5ch2H:`;u+e'Cv
cloning schemes represented a good approximation of the total universe of genes, and...分析测试百科网AIw7[;RA3~
Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网y&^LcW/{
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网L ce5[GI
Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was
d'tBbD&q'M4NH6c}-aJ0the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
mMT'C;O*NCB6n0Cited by 1699-Related articles-BL Direct-All 9 versions

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