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科学家 Patrick O Brown(基因组学)

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Patrick O Brown分析测试百科网9?6`"k1n c"` kk2@
Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
)~!GM0] g_;tX)P0is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网/]#[&dOg{"{ }
in pattern of gene expression. The output is displayed graphically, conveying the...分析测试百科网T F4l3RUfU
Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网uasUI
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com
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Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
P)LvnY/}hx0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
A-`V8IYx Aq0n&r5Cv#B0prolonged survival, whereas the remainder succumb to the disease. We proposed that...
]j]Jk"W7r0Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com分析测试百科网R Q.pP6HY-`
Human breast tumours are diverse in their natural history and in their responsiveness to treatments
YKWc8c+a01 . Variation in transcriptional programs accounts for much of the biological diversity of human分析测试百科网4Y_DLCZh)T
cells and tumours. In each cell, signal transduction and regulatory systems transduce...分析测试百科网,r9y l wlD$W
Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org
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DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
U)Z?S+V'm4DHR0carry out a comprehensive investigation of the temporal program of gene expression accompanying
([1ytL@RS2NB5Y0the metabolic shift from fermentation to respiration. The expression profiles observed for...
~j&?3uQW'bD5h0Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol分析测试百科网?2Z m"}l#H;H
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance分析测试百科网d5Pc.pU
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
Wx%g)\j3w)q}0regulated have been identified using traditional methods, and it was estimated that some...
7H!c e T!y"Y`F`@B0Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences分析测试百科网v@/L#]-?Q J
The purpose of this study was to classify breast carcinomas based on variations in gene expression分析测试百科网0y/wMC(?`b
patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical
f]3?#@0P1I$}K0outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...分析测试百科网.nM4WS/~_wH
Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网C*ED"N9P [H-}o
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding分析测试百科网9jf#Y{X$O/~ yz
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.分析测试百科网|O$Rh w0iI
levels over time for almost every yeast gene, as cells responded to temperature shocks,...
C2tr*Ty$_(J7i0Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn分析测试百科网;ck{6dP^to
The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网O,dHGO_!m#ZG"d b4g
for biologists to imagine that the genes that had been discovered via mutations, selections and
{vj*M4?g oc0cloning schemes represented a good approximation of the total universe of genes, and...分析测试百科网E"W D T_q
Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网k U/N ~0tr K
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
6HV Q8Z-d F9E(P0Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was
j!N_&OMRx0the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...分析测试百科网cci/A*?
Cited by 1699-Related articles-BL Direct-All 9 versions

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