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科学家 Patrick O Brown(基因组学)

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分析测试百科网2v i _z:@fK K

Patrick O Brown
4g'V,k#Jey+N0Biochemistry and HHMI, Stanford University, Stanford, USA

分析测试百科网'zPg.@Y%rHv
Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences分析测试百科网@7qe s@EU3qZ
A system of cluster analysis for genome-wide expression data from DNA microarray hybridization分析测试百科网$y`;P*WU"Ik
is described that uses standard statistical algorithms to arrange genes according to similarity
Co\ U1HOC0A3}0in pattern of gene expression. The output is displayed graphically, conveying the...
b;AYP1iLo0Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网I'Ao+]B7A;d
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com
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Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
3h xeV Z0G6lbb3?0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have分析测试百科网'S3P-\m-{
prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网0`%CT)S9C4bNFV,iL^
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com分析测试百科网(I1EC"z a
Human breast tumours are diverse in their natural history and in their responsiveness to treatments分析测试百科网!w$r]4Np*y nK \g_
1 . Variation in transcriptional programs accounts for much of the biological diversity of human
e x4P!v._0cells and tumours. In each cell, signal transduction and regulatory systems transduce...分析测试百科网 pC.S8Lq
Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org分析测试百科网/iDX2`!vixF
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
5?7M.k$xIQIW0carry out a comprehensive investigation of the temporal program of gene expression accompanying分析测试百科网z/Y ru*]WAK
the metabolic shift from fermentation to respiration. The expression profiles observed for...分析测试百科网C6Ssmao7S2[ E-gZ
Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol分析测试百科网pC~L&nmW,q
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
9M2VTu"H1]D/E1U0during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
!k8c c8y7D0regulated have been identified using traditional methods, and it was estimated that some...
8j?rw+o&Z'X0Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences分析测试百科网{*oJU9gf b
The purpose of this study was to classify breast carcinomas based on variations in gene expression分析测试百科网+i"nyq5`xMK"bW bg
patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical
%t'S)N["w6_e'E8^0outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...
&JG hEmP0Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol
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We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
2y4xZ9h4a0to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
#W1E&MYu6e0levels over time for almost every yeast gene, as cells responded to temperature shocks,...
/eSXh%] a0Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible
(z Bu6lK*L7x0for biologists to imagine that the genes that had been discovered via mutations, selections and
_1BXQ E#}0cloning schemes represented a good approximation of the total universe of genes, and...分析测试百科网G#kA(|k p}5s(x;j.v:|r
Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网'j-m7I.FnuI
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
a P%lN^(|*v(UI0Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was
G6Eezg(ew'O0the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
K_7nnFv q1i0Cited by 1699-Related articles-BL Direct-All 9 versions

分析测试百科网0Kv#a'x t{

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