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科学家 Patrick O Brown(基因组学)

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分析测试百科网8wW!\'Z,Q&l E/noD

Patrick O Brown分析测试百科网KT CL3AuQs
Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization分析测试百科网:@&pEe*y,fp"q
is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网LBB4{ d
in pattern of gene expression. The output is displayed graphically, conveying the...分析测试百科网9}0^.IpQR,P2z
Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网&\ {!]f%u7c(n/q
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com
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Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
$eW-d EM$s*q dd(u0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
7Ud8C~PM,c'X0prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网*Rz!I\r5H]%g
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com
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Human breast tumours are diverse in their natural history and in their responsiveness to treatments分析测试百科网4qPq1]/ZC
1 . Variation in transcriptional programs accounts for much of the biological diversity of human分析测试百科网&z#be _J'ZQcO?
cells and tumours. In each cell, signal transduction and regulatory systems transduce...分析测试百科网V+gWqqYE1vF
Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org分析测试百科网Sd1[ @ t(cX
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
Y2k)fXU7]0carry out a comprehensive investigation of the temporal program of gene expression accompanying
'E9A!w%Wm!g0the metabolic shift from fermentation to respiration. The expression profiles observed for...分析测试百科网 ^pT:o-EO;truh
Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
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In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
@g\i8b0during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle分析测试百科网zM#qkq^}l
regulated have been identified using traditional methods, and it was estimated that some...分析测试百科网/n!U K'vE"hi+ab7x
Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
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The purpose of this study was to classify breast carcinomas based on variations in gene expression
~]:f4O9Hn |x0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical分析测试百科网7u1b*QB3H[
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...分析测试百科网4N#w*~a+?1hA
Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网#s8M"kdA8vb5|
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
Hh!YO!fY0to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
5BnJ6^ j0levels over time for almost every yeast gene, as cells responded to temperature shocks,...分析测试百科网 P R;W \o
Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网%UC+W W ]:V]Mo
for biologists to imagine that the genes that had been discovered via mutations, selections and分析测试百科网"f*Qf+_Fm EeF%K
cloning schemes represented a good approximation of the total universe of genes, and...
Xv-rO^t0Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网/UY"b I9] B4b*[
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
b!H.HB2ky9m n0Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was分析测试百科网gLfR'lx3nR4t
the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
l4HY.a x?F0Cited by 1699-Related articles-BL Direct-All 9 versions

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