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科学家 Patrick O Brown（基因组学）
上一篇 / 下一篇 2010-07-22 14:15:50/ 个人分类：基因治疗实验
| 分析测试百科网G?4t+L BF |
Patrick O Brown分析测试百科网/p,w3?@!J$L |
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| Head of Section: Genomics & Genetics > Genomics [ since 18 July 2001 ] |
部分论著与科研绩效：
http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0
pnas.org [HTML]MB Eisen, PT Spellman, PO Brown, … - Proceedings of the …, 1998 - National Acad Sciences
,O,`6v;IB4N%_&| k2`0A system of cluster analysis for genome-wide expression data from DNA microarray hybridization 分析测试百科网-F Pw+@[&i{ m
is described that uses standard statistical algorithms to arrange genes according to similarity
tQ v g}nV u!F0in pattern of gene expression. The output is displayed graphically, conveying the ...
6zp)N-qg4AJ%Z0Cited by 9913 - Related articles - BL Direct - All 187 versions
,O,`6v;IB4N%_&| k2`0A system of cluster analysis for genome-wide expression data from DNA microarray hybridization 分析测试百科网-F Pw+@[&i{ m
is described that uses standard statistical algorithms to arrange genes according to similarity
tQ v g}nV u!F0in pattern of gene expression. The output is displayed graphically, conveying the ...
6zp)N-qg4AJ%Z0Cited by 9913 - Related articles - BL Direct - All 187 versions
[CITATION] Quantitative monitoring of gene expression patterns with a complementary DNA microarray
Cited by 6923 - Related articles - BL Direct - All 22 versions
cmu.edu [PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, PO Brown, … - Nature, 2000 - nature.com分析测试百科网-h Y!H d k^.]
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's 分析测试百科网!i ` Ui N"me.v {
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
S-nc0_2I LG0prolonged survival, whereas the remainder succumb to the disease. We proposed that ... 分析测试百科网uuf Sur nX
Cited by 5096 - Related articles - BL Direct - All 82 versions
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's 分析测试百科网!i ` Ui N"me.v {
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
S-nc0_2I LG0prolonged survival, whereas the remainder succumb to the disease. We proposed that ... 分析测试百科网uuf Sur nX
Cited by 5096 - Related articles - BL Direct - All 82 versions
… , SX Zhu, PE Lønning, AL Børresen-Dale, PO Brown, D … - Nature, 2000 - nature.com分析测试百科网)x#L/Vt"{
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Human breast tumours are diverse in their natural history and in their responsiveness to treatments
eWI~8LJG01 . Variation in transcriptional programs accounts for much of the biological diversity of human
4ZJ)}.| t#]p i0cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
GM?(b4Y @D H RD0Cited by 3713 - Related articles - BL Direct - All 12 versions
Human breast tumours are diverse in their natural history and in their responsiveness to treatments
eWI~8LJG01 . Variation in transcriptional programs accounts for much of the biological diversity of human
4ZJ)}.| t#]p i0cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
GM?(b4Y @D H RD0Cited by 3713 - Related articles - BL Direct - All 12 versions
ramapo.edu [PDF]JL DeRisi, VR Iyer, PO Brown - Science, 1997 - sciencemag.org分析测试百科网ej.j? u#a%K~)a^3{
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DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to 分析测试百科网0X.Z*n%[u8z^$A7P;@
carry out a comprehensive investigation of the temporal program of gene expression accompanying 分析测试百科网-y(E$djG(|
the metabolic shift from fermentation to respiration. The expression profiles observed for ... 分析测试百科网 sW}w i8D F
Cited by 3645 - Related articles - BL Direct - All 91 versions
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to 分析测试百科网0X.Z*n%[u8z^$A7P;@
carry out a comprehensive investigation of the temporal program of gene expression accompanying 分析测试百科网-y(E$djG(|
the metabolic shift from fermentation to respiration. The expression profiles observed for ... 分析测试百科网 sW}w i8D F
Cited by 3645 - Related articles - BL Direct - All 91 versions
molbiolcell.org [HTML]… , MB Eisen, PO Brown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
T7^h ^ G k,c0In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance 分析测试百科网4_9w LO P @0n
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
o ^tZ km1Rv0regulated have been identified using traditional methods, and it was estimated that some ...
/w w \ E"oB ZD0Cited by 3383 - Related articles - BL Direct - All 84 versions
T7^h ^ G k,c0In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance 分析测试百科网4_9w LO P @0n
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
o ^tZ km1Rv0regulated have been identified using traditional methods, and it was estimated that some ...
/w w \ E"oB ZD0Cited by 3383 - Related articles - BL Direct - All 84 versions
pnas.org [HTML]… JC Matese, PO Brown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
I'D \o My P;H0The purpose of this study was to classify breast carcinomas based on variations in gene expression
,R7A1w y%`-c0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical 分析测试百科网1eCn4Nu
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ... 分析测试百科网 o n@y+Jm'|k Z
Cited by 2902 - Related articles - BL Direct - All 31 versions
I'D \o My P;H0The purpose of this study was to classify breast carcinomas based on variations in gene expression
,R7A1w y%`-c0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical 分析测试百科网1eCn4Nu
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ... 分析测试百科网 o n@y+Jm'|k Z
Cited by 2902 - Related articles - BL Direct - All 31 versions
molbiolcell.org [HTML]… , MB Eisen, G Storz, D Botstein, PO Brown - Molecular biology of …, 2000 - Am Soc Cell Biol
Md8G&I$Zocb U,V0We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding 分析测试百科网,Q+v@8APY-h@
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
l fu})} sg0levels over time for almost every yeast gene, as cells responded to temperature shocks, ...
0X S1vvM*J.zk n0Cited by 2151 - Related articles - BL Direct - All 54 versions
Md8G&I$Zocb U,V0We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding 分析测试百科网,Q+v@8APY-h@
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
l fu})} sg0levels over time for almost every yeast gene, as cells responded to temperature shocks, ...
0X S1vvM*J.zk n0Cited by 2151 - Related articles - BL Direct - All 54 versions
ctu.edu.vn [PDF]PO Brown, D Botstein - nature genetics, 1999 - ctu.edu.vn
M.|S`/AA K0The genome project has revitalized exploration in biological research. Not long ago, it was possible 分析测试百科网 ~5~%qI _a
for biologists to imagine that the genes that had been discovered via mutations, selections and
N!N ^{*v0cloning schemes represented a good approximation of the total universe of genes, and ... 分析测试百科网&x5C-u+F CV\/I)ij
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
M.|S`/AA K0The genome project has revitalized exploration in biological research. Not long ago, it was possible 分析测试百科网 ~5~%qI _a
for biologists to imagine that the genes that had been discovered via mutations, selections and
N!N ^{*v0cloning schemes represented a good approximation of the total universe of genes, and ... 分析测试百科网&x5C-u+F CV\/I)ij
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
stanford.edu [PDF]J DeRisi, L Penland, PO Brown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu
W/A0qH"l Di0... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网#Mq4\!d NBR6D{
Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
%f&f m2F EN0the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ... 分析测试百科网9`q1KiJ+N'EE9@
Cited by 1699 - Related articles - BL Direct - All 9 versions
W/A0qH"l Di0... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网#Mq4\!d NBR6D{
Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
%f&f m2F EN0the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ... 分析测试百科网9`q1KiJ+N'EE9@
Cited by 1699 - Related articles - BL Direct - All 9 versions
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