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科学家 Patrick O Brown(基因组学)

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Patrick O Brown
,})cuYRLsc-d0Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
Th~3Cc2l4u)FF0is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网9_t4\(D9[9eBPd
in pattern of gene expression. The output is displayed graphically, conveying the...
1[EUk| S0Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网B|[ZO3}{Q
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com分析测试百科网NqFk kCZF ~
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
0q+ao6[2T%L4P#F0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
x:Z7i6WEg#x"I0prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网!O2NBU$U:S(b2c j
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com
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Human breast tumours are diverse in their natural history and in their responsiveness to treatments分析测试百科网.u"N#r:FlC;{4w1UnS
1 . Variation in transcriptional programs accounts for much of the biological diversity of human
m"IG7` C&t,c'Qh0cells and tumours. In each cell, signal transduction and regulatory systems transduce...
R$gXUC/J~@ J{e0Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org
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DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to分析测试百科网x,T@ h|+wT
carry out a comprehensive investigation of the temporal program of gene expression accompanying
*B~8D4^0GfV7g0the metabolic shift from fermentation to respiration. The expression profiles observed for...分析测试百科网o j9W5v#L}
Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol分析测试百科网t0t-_ O nl$@4E9F
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance分析测试百科网lyQ:{^`5O_
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
d/Xj;Kz @0regulated have been identified using traditional methods, and it was estimated that some...
r5o pn u+h)HX0Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences分析测试百科网6{+Q4Aa1dAx[2t
The purpose of this study was to classify breast carcinomas based on variations in gene expression
A+p"j'e p"{0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical分析测试百科网+{m-I1T*pK
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...
!T8k"}V2uA5[dr0Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网$S y?VB"T;gG K
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding分析测试百科网nNG;t8J\y;C w sg
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.分析测试百科网'yQ/q9a9s9Fb
levels over time for almost every yeast gene, as cells responded to temperature shocks,...
U aK ~L0W:kpE0Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn分析测试百科网F m"Y]uK(A~
The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网6k9c@T,t'p(nVY:S
for biologists to imagine that the genes that had been discovered via mutations, selections and分析测试百科网9Z4_ a1d"iQ"P4G
cloning schemes represented a good approximation of the total universe of genes, and...
q:mF6K"x$~)r0Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu
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...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网3F j8N4aJ?HG^S%D
Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was
bg5t)`"p%S`G%]x0the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
*s'P3TL7h U"Hn0Cited by 1699-Related articles-BL Direct-All 9 versions

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