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科学家 Patrick O Brown(基因组学)

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Patrick O Brown分析测试百科网5G0and a1DG R
Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
B!P-W K^)Fe5~0is described that uses standard statistical algorithms to arrange genes according to similarity
&{ ]3Uo0Fhgs0in pattern of gene expression. The output is displayed graphically, conveying the...分析测试百科网O6Y%w$X/c&R(y'L/WD2X z
Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网8Mw"G2V4{tU'u
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com分析测试百科网"p/v%HE*qI!m |3u
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's分析测试百科网#c*U~~B"s7wud
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have分析测试百科网+? | \'~8Rm;f6r D@
prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网,q1w"p(t-}
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com分析测试百科网4sVFT'eWcl
Human breast tumours are diverse in their natural history and in their responsiveness to treatments
r2G d)Jc5f/E01 . Variation in transcriptional programs accounts for much of the biological diversity of human分析测试百科网0@-u n%z&Sa
cells and tumours. In each cell, signal transduction and regulatory systems transduce...
v Atl9\0Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org
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DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
dE]&g'I{ ye T0carry out a comprehensive investigation of the temporal program of gene expression accompanying分析测试百科网GK-lao \ hj~Wv:Th^
the metabolic shift from fermentation to respiration. The expression profiles observed for...
^c+_X MfeI@[0Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
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In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
%d \O0cL]xL P4C#c0during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
;w/K F7wa$LX6sG0regulated have been identified using traditional methods, and it was estimated that some...
Y!W\6aP;pF0Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
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The purpose of this study was to classify breast carcinomas based on variations in gene expression分析测试百科网r a;i,e ]6v
patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical分析测试百科网m%y9^\,X`UZ`,o
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...分析测试百科网S!Jh ?6B~ J;W&Gg"o
Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol
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We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
:^(gJpa"|0QY-i0to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.分析测试百科网Z(\;H RX}?
levels over time for almost every yeast gene, as cells responded to temperature shocks,...
R(|@'t"t;].I I AE VM0Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible
(aS-|8{P*b!@4Y{0for biologists to imagine that the genes that had been discovered via mutations, selections and分析测试百科网2CS |8T%l?(Q
cloning schemes represented a good approximation of the total universe of genes, and...
&] wt W'W3P q0Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网^WwCP+Mm2`1_J)v
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
CN(u)F B3\l0Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was分析测试百科网5{r U8B0w
the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
(s]@]6K0Cited by 1699-Related articles-BL Direct-All 9 versions


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