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科学家 Patrick O Brown(基因组学)

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Patrick O Brown
+R&iQv YE'L9BTY%RY0Biochemistry and HHMI, Stanford University, Stanford, USA

分析测试百科网2Yf2|,|w.L)N&N0h
Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
V+}U6Sr_9ql)P0Jz0is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网7p iw Q_|'trT}
in pattern of gene expression. The output is displayed graphically, conveying the...分析测试百科网H`(A:f\-E_5]dv?{8p
Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS分析测试百科网/xQ!Bb [D%E
Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com分析测试百科网;Lx1@#e/F"qJ
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's分析测试百科网 J;qd.}:~wpbqg
lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have分析测试百科网4{Nb ^f'Iz
prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网fQ |D|B"G
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com
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Human breast tumours are diverse in their natural history and in their responsiveness to treatments
:`T*y0gD6C01 . Variation in transcriptional programs accounts for much of the biological diversity of human分析测试百科网j+B*JY,a
cells and tumours. In each cell, signal transduction and regulatory systems transduce...分析测试百科网Jx)rK4]
Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org分析测试百科网%z_.GT/bzTQ(E
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to分析测试百科网:hXYI| KkG^@
carry out a comprehensive investigation of the temporal program of gene expression accompanying分析测试百科网'h,O#\ c7vW St!G
the metabolic shift from fermentation to respiration. The expression profiles observed for...
T V;h4RG6b6e0Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
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In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance分析测试百科网5X o6jX+vgE2\
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
0k@H}}s%F1N-G1nf0regulated have been identified using traditional methods, and it was estimated that some...分析测试百科网dh%ETf3c
Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences分析测试百科网 ^rC0R,}K ^S%nL
The purpose of this study was to classify breast carcinomas based on variations in gene expression
/W:xd&RG&a0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical
I lg9F(ZPT%E/a%r/F0outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...分析测试百科网Y|U3O:[~:Cv b
Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网-W ?:~oPy;o{ I
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding分析测试百科网/_%eG([y P"H2u,j
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.分析测试百科网p~-@^\
levels over time for almost every yeast gene, as cells responded to temperature shocks,...
v](_GZ4b n0Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网P?1s Gg
for biologists to imagine that the genes that had been discovered via mutations, selections and
z*C]3P7[D G0cloning schemes represented a good approximation of the total universe of genes, and...分析测试百科网5AK4M6bpy(r
Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网IA RN{*|7|*lb8mM
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网 Dz$B7p3d"z/h c,J#XH2J
Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was分析测试百科网b5?*i#`G u6Z0lF
the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...
k}jfWE0Cited by 1699-Related articles-BL Direct-All 9 versions


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