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科学家 Patrick O Brown(基因组学)

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Patrick O Brown
'w6rrO @0];\ x3p#G;B0Biochemistry and HHMI, Stanford University, Stanford, USA


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Head of Section:Genomics & Genetics > Genomics [ since 18 July 2001 ]

部分论著与科研绩效:

http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0

pnas.org[HTML]MB Eisen, PT Spellman, POBrown, … - Proceedings of the …, 1998 - National Acad Sciences
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A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
e7z;y2\~*[.g"X(ng0is described that uses standard statistical algorithms to arrange genes according to similarity分析测试百科网e5i0h^/@ w%?
in pattern of gene expression. The output is displayed graphically, conveying the...
4V)H`E lU0Cited by 9913-Related articles-BL Direct-All 187 versions

 

[CITATION]Quantitative monitoring of gene expression patterns with a complementary DNA microarray

ensmp.fr[PDF]M Schena, D Shalon, RW Davis, POBrown- Science, 1995 - AAAS
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Cited by 6923-Related articles-BL Direct-All 22 versions

 

cmu.edu[PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, POBrown, … - Nature, 2000 - nature.com
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Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
"{ CF9A!|2Z \(dy;?0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have
%a#t4w/} z!Uv0prolonged survival, whereas the remainder succumb to the disease. We proposed that...分析测试百科网.g/cao,{Q!kDl
Cited by 5096-Related articles-BL Direct-All 82 versions

 

… , SX Zhu, PE Lønning, AL Børresen-Dale, POBrown, D … - Nature, 2000 - nature.com分析测试百科网X tj5p2t0x4]so"`'P
Human breast tumours are diverse in their natural history and in their responsiveness to treatments分析测试百科网.Zpn5s2e&k
1 . Variation in transcriptional programs accounts for much of the biological diversity of human
LT.H }n*^gh0cells and tumours. In each cell, signal transduction and regulatory systems transduce...
I5rA u Vj XL}-}0Cited by 3713-Related articles-BL Direct-All 12 versions

 

ramapo.edu[PDF]JL DeRisi, VR Iyer, POBrown- Science, 1997 - sciencemag.org分析测试百科网%k5` RO\ g$m3~sc
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
lUK8e7Q#Rpxc0carry out a comprehensive investigation of the temporal program of gene expression accompanying分析测试百科网nL ~a4u/j"_2F:yk
the metabolic shift from fermentation to respiration. The expression profiles observed for...
5{2d-Y6rv2@#V0Cited by 3645-Related articles-BL Direct-All 91 versions

 

molbiolcell.org[HTML]… , MB Eisen, POBrown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol
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In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance
A,m,_.y3^T0during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle分析测试百科网|5wa] d3[
regulated have been identified using traditional methods, and it was estimated that some...分析测试百科网E }L!z Q/`R
Cited by 3383-Related articles-BL Direct-All 84 versions

 

pnas.org[HTML]… JC Matese, POBrown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences分析测试百科网Z\M]Kcc
The purpose of this study was to classify breast carcinomas based on variations in gene expression
@I BhPY0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical分析测试百科网)`7v&_;iQ!^s3z
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three...
"e&\|(\*E0Cited by 2902-Related articles-BL Direct-All 31 versions

 

molbiolcell.org[HTML]… , MB Eisen, G Storz, D Botstein, POBrown- Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网 Pf&q!i$U|
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding分析测试百科网^:n#ms)`
to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
D6m9m ]/]5vF`0levels over time for almost every yeast gene, as cells responded to temperature shocks,...分析测试百科网I?~6F6e/rF2o DQh
Cited by 2151-Related articles-BL Direct-All 54 versions

 

ctu.edu.vn[PDF]POBrown, D Botstein - nature genetics, 1999 - ctu.edu.vn
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The genome project has revitalized exploration in biological research. Not long ago, it was possible分析测试百科网`+Y5i j:FAe
for biologists to imagine that the genes that had been discovered via mutations, selections and
L9o)ke j^7SP0cloning schemes represented a good approximation of the total universe of genes, and...分析测试百科网c4X],@q ~!B dp1ME&C
Cited by 1919-Related articles-View as HTML-BL Direct-All 82 versions

 

stanford.edu[PDF]J DeRisi, L Penland, POBrown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网 L$T(p,OCy
...microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita分析测试百科网xB8mr2s8a
Penland2 &PatrickО...with significantly higher expression (>10-fold) in the tumorigenic cells was
K.K zO!x.o7L0the humanbrownlocus pro...Filters were washed to a strin- gency ofO.lx SSC at 42 °C for 20...分析测试百科网k+q8WyKx
Cited by 1699-Related articles-BL Direct-All 9 versions


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