药片样品中五味子醇，五味子醇甲，五味子醇乙的分离

摘要：

Schisandra chinensis (Turcz.) Baill is an important traditional Chinese medicine believed to be an anticarcinogen and provide hepatoprotection, among other attributes. Its major active components are lignanoids, and the three major lignanoids are schizandrin, schizandrin A, and schizandrin B1 (structures shown in Figure 1). Hugan tablets, which contain Schisandra chinensis (Turcz.) Baill, are a traditional Chinese medicine for hepatoprotection. The Pharmacopoeia of the People’s Republic of China (PPRC) 2010 regulates its quality control with a UHPLC method for the determination of schizandrin, schizandrin A and schizandrin B.

仪器：

Thermo Scientific Dionex UltiMate 3000 快速液相色谱系统

结论：

Put 0.7 g of sample powder to 25 mL of water-saturated ethyl acetate, and weigh the mixture. Ultrasonically extract (500 W and 60 KHz) for 30 min. After the solution cools to room temperature, replace the lost weight with ethyl acetate. After filtering, dry 15 mL of filtrate using a rotary evaporator. Dissolve the residue in 5 mL methanol.