LESA应用于比较脂质组学分析
发布时间:
2014-03-12 16:42
来源:华质泰科生物技术(北京)有限公司
资料文件名 |
下载 |
TVNM_AppNote_LESA.pdf |
下载此篇资料 |
Application Note
Lipidomics
Evaluating Liquid Extraction Surface Analysis (LESA) for Comparative Lipidomics Profiling
Introduction
Professor Manuel Mayr and his group at the King’s British Heart Foundation Center of King’s College London evaluated liquid
extraction surface analysis (LESA) compared to previously published tissue extraction techniques. The TriVersa NanoMate LESA
capability was employed to provide automated and efficient sampling. In addition, it allowed for easy analysis of one sample to act as its
own control. The group was able to evaluate the ionization efficiency in both negative and positive mode, thereby increasing the amount
of information obtained.
By comparing LESA to previously published tissue extraction technique of shotgun lipidomics, the group was able to show comparable and often times better data without sample preparation, thereby saving time and money.
质谱:TSQ Vantage三重四极杆,nanomate
结论:
-
Liquid extraction surface analysis (LESA) is a rapid approach to tissue analysis without sample preparation time and effort.
-
Shotgun lipidomics provides valuable insights into the relationship within artherosclerotic plaques.
-
LESA and other advanced mass spectrometry techniques can be employed for diagnostic and drug screening applications due to their complete profiling of lipid species and classes.
相关产品
-
品牌: 华质泰科
-
品牌: 华质泰科
-
品牌: 华质泰科
-
品牌: 华质泰科
-
品牌: 华质泰科