amaZon speed离子阱质谱仪

amaZon speed不仅仅是世界上速度zei快的离子阱，更是具备zei高质量精度和分辨率的离子阱。

amaZon speed所有的扫描模式均提供了显著提高的分辨率：

扫描速度zei快的XtremeScan (52,000 u/sec)模式，

对于双电荷离子提供优于0.5u的高质量分辨率；

zei大分辨模式(5,200 u/sec)能将质量分辨率控制在远低于0.1u的水平，可以在全扫描方式（质荷比高达3000）下分辨8价离子。

amaZon speed在硬件和软件上的另一重要改进使得MS/MS周期达到8Hz。

Unmatched ion trap performance through innovation

• Greatly increased MS/MS duty cycle for more productive data acquisition

• Further improved resolution on a market-leading system with an unrivalled  value of 30,000 in full scan

• Highest ion trap mass accuracy through proprietary RF generator design

• Unrivalled ETD performance: most sensitive, robust and reliable technology

• Leading dual ion funnel technology for unparalleled sensitivity

• Zero Delay Alternating™ for polarity switching with 20 Hz MS acquisition speed

• New SMART isolation and fragmentation

Technology driven solutions

• SmartFrag™ for reproducible MS/MS spectra generation and confident library searches

• Zero Delay Alternating™ polarity for up to 20 Hz MS acquisition speed supporting UHPLC applications

• Dual ion funnel for maximum sensitivity over a broad m/z range

• Patented SmartICC™ for optimal ion storage

• SMART isolation and SMART fragmentation

• Panorama fragmentation (PAN) enabling CID fragmentation without 1/3 cutoff

MS/MS modes

• Data-dependent auto MSn

• Preferred mass lists for automated feedback experiments from MetaboliteTools and ProteinScape

• Scheduled precursor lists supporting MS2, MS3

• in positive and negative mode

• Neutral loss scans for analysis of target compounds and posttranslational

• modifications (by ETD)

• Multiple reaction monitoring (MRM) for drug quantification

• Manual MSn up to MS11

• in all scan modes for structural elucidation

• Highly efficient and sensitive ETD/PTR capabilities for PTM detection and

• Top-down proteomics

Source options

• ESI, APCI, APPI

• DIP source for direct analysis of solids and liquids

• CaptiveSpray: robust and reliable plug-and-play nano/cap ESI source for

• flow rates from 50-5000 nl/min

• Advion Triversa NanoMate

• Smart CE-MS coupling with grounded spray needle

Software solutions

• ProteinScape including GlycoQuest glycan DB search engine

• RapiDeNovo for de-novo sequencing of proteins

• MetaboliteTools for metabolite prediction and identification

• ProfileAnalysis for statistical comparison of metabolite and proteomic profiles

• Compass OpenAccess client server based system for walk-up users

• Compass Security Pack for work in regulated environments

• ACD/MS Manager for structural interpreation and classification

m/z范围：50~3000 amu，可扩展到6000 amu

灵敏度：250 fg利血平，信噪比500:1

分辨率：在50~3000 amu内zei高可到20,000 FWHM（相当于0.15 u）

谱图采集速度：zei高20 Hz

MS级数：自动5级，手动11级

扫描速度：52,000 amu/sec，并保持分辨率在0.58u

零延迟的极性转换

双离子漏斗设计

超高性能的高容量离子阱与zei新的离子漏斗式传输技术

• SmartI CC™zl技术优化离子储存功能

• 在MS和MS/MS模式下，均可获得高分辨率、超快扫描速度和质量范围

• 正负离子在线数据采集，正负模式无延迟切换

• Smart Frag™为成功的谱库检索提供了高重现性的二级质谱图

• 全景解离（PAN）：不受常规离子阱1/3低质量范围限制（1/3 cut-off）的CID解离技术

• 电子转移解离（ETD）和质子转移反应（PTR）碎裂形式

扫描模式

• 在所有扫描模式下，可以手动完成高达11级质谱（MS11） 

• 自动MSn实验，在MS模式下zei多可选择30个前体离子，在每级多级模式下zei多可选择5个碎片离子作为前体离子 

• 中性丢失扫描，用于蛋白质修饰确认 

• MS/MS和MS3模式下多反应检测（MRM）

数据依赖实验

• 各种类型的数据依赖实验，包括从MetaboliteTools和PROTEINEER得到的首选质量列表的自动反馈实验。

可选离子源

• 电喷雾离子源，大气压化学电离源，大气压光电离源，复合离子源，HPLC-Chip，Advion Triversa NanoMate，在线/离线纳升喷雾离子源，通过接地的ESI喷针和毛细管电泳联用的CE-MS接口

可选软件 

• MetaboliteTools™代谢产物鉴定

• BioTools™/RapiDeNovo™蛋白质数据解析

• ProteinScape™蛋白质组项目管理数据库系统

• ACD/MS Menager™用于结构分析和分类

• Compass Security Pack法规遵循

• Compass OA/QC：为使用者提供以网络为基础的LCMS使用指南