一本领先的国际同行评审生物医学研究期刊，发表化学、生物学、药理学、基因组学和医学等领域交叉主题的文章，面向参与药物设计、发现和开发、目标识别和验证的科学家和研究人员，以及常见以及罕见和被忽视的疾病和病症的治疗方法的临床前和临床开发。该杂志出版的专着包含有关正在开发的新化合物的全面产品信息，包括合成、临床前药理学、药代动力学和代谢、安全性、临床研究和药物相互作用，以及有关各种主题、大会和会议报告的评论文章。

A leading international, peer-reviewed biomedical research journal publishing articles on topics emerging from the confluence of fields including chemistry, biology, pharmacology, genomics and medicine, and addressed to scientists and researchers involved in drug design, discovery and development, target identification and validation, and the preclinical and clinical development of treatments for common as well as rare and neglected diseases and conditions. The journal publishes monographs containing comprehensive product information on new compounds in development, including synthesis, preclinical pharmacology, pharmacokinetics and metabolism, safety, clinical studies and drug interactions, as well as review articles on a variety of topics, congress and meeting reports.