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发育与疾病相关基因教育部重点实验室

发育与疾病相关基因教育部重点实验室

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近年本重点试验发表文章

序号 论文名称 作  者
(*为通讯作者)
发表刊物 年、卷、期、页
1

Identification of a novel HLA class I allele, HLA-Cw*0134 in a Chinese individual

F. Miao, H. Sun, N. Pan, Y. Shen, W. Xie & J. Zhang*

Tissue Antigens

2010 75(6):  737–U84

2

A transgenic Cre mouse line for the study of cortical and hippocampal development.

Zhou W, Zhang Y, Li Y, Wei YS, Liu G, Liu DP, Pleasure SJ, Xie W, Zhao C*

Genesis

201005,48(5):343-350

3

Confirmation of the combinational effects of calcium with other metals in a paper recycling mill effluent on nematode lifespan with the toxicity identification evaluation method.

Dayong Wang*, Yang Wang, Lulu Shen

Journal of Environmental Sciences

2010, 22(5): 731-737.

4

Depletion of DNMT3A suppressed cell proliferation and restored PTEN in hepatocellular carcinoma cells.

Zhao Z, Wu Q, Cheng J, Qiu X, Zhang J, Fan H*

Journal of Biomedicine and Biotechnology

2010, 2010;2010:737535.

5

Pre-treatment with mild UV irradiation increases the resistance of nematode Caenorhabditis elegans to toxicity on locomotion behaviors from metal exposure.

Dayong Wang*, Peidang Liu, Xiaojuan Xing

Environmental Toxicology and Pharmacology

2010, 29(3): 213-222.

6

DNMT3B promoter polymorphism and risk of gastric cancer.

Hu J, Fan H, Liu D, Zhang S, Zhang F, Xu H

Digestive Diseases and Sciences

2010 Apr;55(4):1011-1016

7

Genes required for the functions of olfactory AWA neuron regulate the longevity of Caenorhabditis elegans in an insulin/IGF signaling-dependent fashion.

Lulu Shen, Min Du, Xingfeng Lin, Ting Cai, Dayong Wang*

Neuroscience Bulletin

2010, 26(2): 91-103.

8

Interleukin-15 receptor-directed immunotoxins atteunuate disease severity in rat adjuvant arthritis.

Deling Wang, Xianglei Deng, Xiaoyan Leng, Xiaohua Mao*

Molecular Immunology

2010, 47(7-8):1535-1543

9

UNC-64 and RIC-4, the plasma membrane associated SNAREs syntaxin and SNAP-25, regulate fat storage in nematode Caenorhabditis elegans.

Qiuli Wu, Qi Rui, Kewen He, Lulu Shen, Dayong Wang*

Neuroscience Bulletin

2010, 26(2): 104-116

10

Expression pattern and clinical significance of DNA methyltransferase 3B variants in gastric carcinoma.

Su X, Lv C, Qiao F, Qiu X, Huang W, Wu Q, Zhao Z, Fan H*

Oncology Reports

2010; 23(3): 819-826.

11

Localized expression pattern of miR-184 in Drosophila

Ping Li, Jianjian Peng,  Jiangbo Hu, Zhongxin Xu, Wei Xie,  Liudi Yuan*

Molecular Biology Report

2010 Mar 26 [Epub ahead of print]

12

Pre-treatment with mild UV irradiation suppresses reproductive toxicity induced by subsequent cadmium exposure in nematodes

Dayong Wang, Xiaojuan Xing*

Ecotoxicology and Environmental Safety

2010, 73(3): 423-429.

13

A functional polymorphism in the DNA methyltransferase 3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma

Fan H*, Liu D, Qiu X, Qiao F, Wu Q, Su X, Zhang F, Song Y, Zhao Z, Xie W

Biomedcentral Medicine

2010;Feb3;8:12

14

Effects of metal exposure on associative learning behavior in nematode Caenorhabditis elegans

Yanfen Zhang, Boping Ye, Dayong Wang.

Archives of Environmental Contamination and Toxicology

2010, doi: 10.1007/s00244-009-9456-y

15

Hypermethylation of HLA class I gene is associated with HLA class I down-regulation in human gastric

Q. Ye, Y. Shen, X. Wang, J. Yang, F. Miao, C. Shen & J. Zhang*

Tissue Antigens

2010 Jan;75(1):30-39

16

Formation of combined Ca/Cd toxicity on lifespan of nematode Caenorhabditis elegans

Dayong Wang*, Peidang Liu, Yichao Yang, Lulu Shen

Ecotoxicology and Environmental Safety

2010, doi: 10.1016/j.ecoenv.2010.05.002

17

Adverse effects of metal exposure on chemotaxis towards water-soluble attractants regulated mainly by ASE sensory neuron in nematode Caenorhabditis elegans

Xiaojuan Xing, Min Du, Yanfen Zhang, Dayong Wang*

Journal of Environmental Sciences

2009. 21(12): 1684-1694

18

Pre-treatment with mild metal exposure suppresses the neurotoxicity on locomotion behavior induced by the subsequent severe metal exposure in Caenorhabditis elegans

Dayong Wang*, Xiaojuan Xing

Environmental Toxicology and Pharmacology

2009, 28(3):459-464

19

The expression pattern of Follistatin-like 1 in mouse central nervous system development

Yang Y, Liu J, Mao H, Hu YA, Yan Y,  Zhao C*

Gene Expression Patterns

2009 Oct; 9(7):532-540

20

The lethality toxicities induced by metal exposure during development in nematode Caenorhabditis elegans

Xiaojuan Xing, Dayong Wang*

Bulletin of Environmental Contamination and Toxicology

2009,83(4):530-536

21

Using the larvae nematode Caenorhabditis elegans to evaluate neurobehavioral toxicity to metallic salts

Xiaojuan Xing, Yuling Guo, Dayong Wang*

Ecotoxicology and Environmental Safety

2009, 72(7): 1819-1823

22

Genetic Interaction between Neurexin and CAKI/CMG Is Important for the Synaptic Function in Drosophila

Mingkuan Sun, Lijuan Liu Xiankun Zeng, Li Liu, Ming fang, Wei Xie*

Neuroscience Research

2009,64(4):362-71 

23

A GAL4/UAS Luciferase System to Identify the miRNAs Target mRNAs in Drosophila S2 cells

Wenwen Lv, Jie Ding, Jiangbo Hu, Chao Wang, Leyi Xu, Ming Fang, Liudi Yuan*

Molecular Biology Report

2009,36(6):1627-1631

24

Exposure to metals induces morphological and functional alteration of AFD neurons in nematode Caenorhabditis elegans

Xiaojuan Xing, Min Du, Xuemei Xu, Qi Rui, Dayong Wang*

Environmental Toxicology and Pharmacology

2009. 28(1): 104-110

25

Induction of chemotaxis to sodium chloride and diacetyl and thermotaxis defects by microcystin-LR exposure in nematode Caenorhabditis elegans

Yunhui Li, Huayue Ye, Min Du, Yanfen Zhang, Boping Ye, Yuepu Pu, Dayong Wang*

Journal of Environmental Sciences

2009. 21(7): 971-979

26

Induction of reproductive deficits in nematode Caenorhabditis elegans exposed to metals at different developmental stages 

Yuling Guo, Yichao Yang, Dayong Wang*

Reproductive Toxicology

2009, 28(1): 90-95

27

Cloning and expression of three peptide-linked β2-microglobulin molecules in Escherichia coli with an isocaudamer technique

Fanyan Meng, Chuanlai Shen,Yong He, Fengqin Miao, Jianqiong Zhang*

Biotechnol Lett

2009 Jun;31(6):831-836

28

Drosophila ptip is essential for anterior/posterior patterning in development and interacts with the PcG and trxG pathways 

Ming Fang*, Hongyan Ren, Jiabin Liu, Ken M. Cadigan, Sanjeevkumar R. Patel and Gregory R. Dressler*

Development

2009 June 1; 136(11): 1929–1938

29

IRF-1 and p65 mediate upregulation of constitutive HLA-A antigen expression by hepatocellular carcin 

Yuqing Shen, Mei Xia, Jianqiong Zhang, Lianhong Xu, Jin Yang, Aiqin Chen, Fengqin Miao, SoldanoFerrone, Wei Xie*

Molecular Immunology

2009,46(10):2045-2053

30

Downregulation of HLA Class I Molecules in Primary Oral Squamous Cell Carcinomas and Cell Lines 

Qiusha Tang, Jianqiong Zhang, Bing Qi, Chuanlai Shen, and Wei Xie*

Archives of Medical Research

2009,40(4): 256-263

31

Exposure to lead and mercury in young larvae induces more severe deficits in neuronal survival and synaptic function than in adult nematodes

Xiaojuan Xing, Qi Rui, Min Du, Dayong Wang*

Archives of Environmental Contamination and Toxicology

2009. 56(4): 732-741

32

The neurotoxic effects of heavy metal exposure on GABAergic system in nematode Caenorhabditis elegans

Min Du, Dayong Wang*

Environmental Toxicology and Pharmacology

2009. 27(3): 314-320

33

Overexpression of DNA methyltransferase 1 and its biological significance in primary hepatocellular

Fan H*, Zhao ZJ, Cheng J, Su XW, Wu QX, Shan YF.

World Journal of Gastroenterology

2009,15(16):2020-2026    

34

Characterization of the Frizzled10-CreER (TM) Transgenic Mouse: An Inducible Cre Line for the Study of Cajal-Retzius Cell Development

Xiaochun Gu, Yan Yan, Hanlin Li, Dongyang He, Samuel J. Pleasure, Chunjie Zhao*

Genesis

2009 Mar; 47(3): 210 – 216.

35

Expression of Frizzled10 in mouse nervous system

Yan Yan, Yiping Li, Chuanyin Hu, Xiaochun Gu, Junhua Liu, Yu-An Hu,Yang Yang, Yiquan Wei, Chunjie Zhao*

Gene Expression Patterns

2009, Mar; 9 (3):173-177 

36

Using the nematode Caenorhabditis elegans as a model animal for assessing the toxicity induced by microcystin-LR

Yunhui Li, Yang Wang, Lihong Yin, Yuepo Pu, Dayong Wang*

Journal of Environmental Sciences

2009, 21(3): 395-401

37

A useful transgenic mouse line for studying the development of spinal nociceptive circuits

Chuanyin Hu, Junhua Liu, Ying Zhang, Yiping Li, Wei Xie, Chunjie Zhao*

Neuroscience Letters

2009,450(2): 211-216    

38

Occurrence of the transition of apical architecture and expression patterns of related genes during conversion of apical meristem identity in G2 pea

Dayong Wang, Qing Li, Keming Cui, Yuxian Zhu*

Journal of Integrative Plant Biology

2009, 51(1): 13-20

39

Inhibition of de novo DNA Methyltransferase 3B is a Potential Therapy for Hepatocellular Carcinoma

Hong Fan*, Jian Cheng, Zhu Jiang Zhao

Gastroen Res

2008,1(1):33-39

40

Regulation of the NMDA receptor-mediated synaptic response by acetylcholinesterase inhibitors and its impairment in an animal model of Alzheimer's disease

Guojun Chen, Paul Chen, Huibing Tan, DaMa, Fei Dou, Jian Feng, Zhen Yan*

Neurobiology of Aging

2008, 29(12):1795-1804

41

Toxicity evaluation in a paper recycling mill effluent by coupling bioindicator of aging with the toxicity identification evaluation method in nematode Caenorhabditis elegans

Xiaoyi Wang, Lulu Shen, Hongxia Yu, Dayong Wang*

Journal of Environmental Sciences

2008, 20(11): 1373-1380

42

Generation of Frizzled10-Cre transgenic mouse line: A useful tool for the study of dorsal telencephalic development

Xiaochun Gu, Dongyang He, Yiping Li, Chuanyin Hu, Yu-sheng Wei, Guang Liu, Depei Liu, Samuel J Pleasure, Wei Xie, Chunjie Zhao*

Genesis

2008, 46(10): 523-529

43

Molecular actions guiding neural regeneration in planarians

Yanfen Zhang, Boping Ye, Dayong Wang*

Neuroscience Bulletin

2008. 24(5): 329-337

44

Assessment of locomotion behavioral defects induced by acute toxicity from heavy metal exposure in nematode Caenorhabditis elegans

Dayong Wang*, Xiaojuan Xing

Journal of Environmental Sciences

2008. 20(9): 1132-1137

45

Expression pattern of Wnt inhibitor factor 1 (Wif1) during the development in mouse CNS

Yu-An Hu, Xiaochun Gu, Junhua Liu, Yang Yang, Yan Yan,  Chunjie Zhao*

Gene Expression Patterns

2008, 8 (7-8): 515-522

46

Phosphorylation of HsMis13 by Aurora B Kinase Is Essential for Assembly of Functional Kinetochore

Yong Yang, Fang Wu, Tarsha Ward, Feng Yan, Quan Wu, Zhaoyang Wang, Trisha McGlothen, Wei Peng, Tianpa You, Mingkuan Sun, Taixing Cui, Renming Hu, Zhen Dou, Jingde Zhu, Wei Xie, Zihe Rao, Xia Ding, and Xuebiao Yao*

Journal of Biological  Chemistry

2008,283(39):26726-26736

47

Loss of heterozygosity at 6p21 underling HLA class I downregulation in Chinese primary esophageal squamous cell carcinomas

Yang Y, Zhang J, Miao F, Wei J, Shen C, Shen Y, Xie W*

Tissue Antigens

2008,72(2):105-114   

48

Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study

Fan H*, Zhang F, Hu J, Liu D, Zhao Z

Journal of Experimental and Clinical Cancer Research   

2008 Jul 28;27(1):24

49

Septin 7 Interacts with Centromere-associated Protein E and Is Required For Its Kinetochore Localization

Mei Zhu, Fengsong Wang, Feng Yan, Phil Y. Yao, Jian Du, Xinjiao Gao, Xiwei Wang, Quan Wu, Tarsha Ward, Jingjing Li, Steve Kioko, Renming Hu, Wei Xie, Xia Ding, and Xuebiao Yao*

Journal of Biological  Chemistry

2008,283(27):18916-18925

50

Trace administration of vitamin E can retrieve and prevent UV-irradiation- and metal exposure-induced memory deficits in nematode Caenorhabditis elegans

Huayue Ye, Boping Ye, Dayong Wang*

Neurobiology of Learning and Memory

2008. 90(1): 10-18

51

Acid phosphatase activity may affect the tuber swelling by partially regulating sucrose-mediated sugar resorption in potato

Dayong Wang*, Yong Lian, Dewei Zhu

Journal of Integrative Plant Biology

2008. 50(6): 733-741

52

Identification of a novel HLA-A allele, HLA-A*9216

Jiang W, Zhang JQ, Pan N, Xu JH, Xie W*

Tissue Antigens

2008 May;71(5):479-80

53

DNMT3B 579 G>T promoter polymorphism and risk of esophagus carcinoma in Chinese

Hong Fan, Dong sheng Liu, Shuhong Zhang, et al.

World Journal of Gastroenterology

2008,14(14):2230-4.

54

Phenotypic and behavioral defects caused by barium exposure in nematode Caenorhabditis elegans

Dayong Wang*, Yang Wang

Archives of Environmental Contamination and Toxicology

2008. 54(3): 447-453

55

PPF1 may suppress plant senescence via activating TFL1 in transgenic Arabidopsis plants.

Dayong Wang*, Qing Li, Keming Cui, Yuxian Zhu

Journal of Integrative Plant Biology

2008. 50(4): 475-483

56

The 5' untranslated region of fruA mRNA is required for translational enhancement of FruA synthesis during Myxococcus xanthus development.

Nianhua Ding, Ying Zheng, Qian Wu, Xiaohua Mao*

Archives of Microbiology

2008,189(3):279–288

57

Evaluation of the long-term memory for thermosensation regulated by neuronal calcium sensor-1 in Caenorhabditis elegans

Huayue Ye, Boping Ye, Dayong Wang*

Neuroscience Bulletin

2008. 24(1): 1-6

58

Molecular control of memory in nematode Caenorhabditis elegans

Huayue Ye, Boping Ye, Dayong Wang*

Neuroscience Bulletin

2008. 24(1): 49-55

59

Nickel sulfate induces numerous defects in Caenorhabditis elegans that can also be transferred to progeny

Dayong Wang*, Yang Wang

Environmental Pollution

2008. 151(3): 585-592

60

DX16 is a novel SR protein phosphorylated by DOA

Yongqi Wan, Mingkuan Sun,  Shanzhi Wang, Li Liu, Liudi Yuan,  Wei Xie*

Molecular and cellular Biochemistry

2008,307(1-2):177-183

61

DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721.

Hong Fan*, Zhujiang Zhao, Yanmei Quan, Jun Xu, JianQiong Zhang, Wei Xie

European Journal of Gastroenterology and Hepatology

2007,19(11):952-61

62

Gibberellin is involved in the Regulation of Cell Death-mediated Apical Senescence in G2 Pea

Dayong Wang, Qing Li, Ke Ming Cui,Yu-Xian Zhu

Journal of Integrative Plant Biology

2007,49(11):1627-1633

63

Multi-biological defects caused by lead exposure exhibit transferable properties from exposed parents to their progeny in Caenorhabditis elegans

Dayong Wang*, Yang Peng

Journal of Environmental Sciences

2007,19(11):1367-1372

64

Mutations in ISDR of NS5A gene influence interferon efficacy in Chinese patients with chronic hepatitis C virus genotype 1b infection

Chuanlai Shen, Ting Hu, Ling Shen, Lei Gao, Wei Xie, Jianqiong Zhang*

Journal of Gastroenterology and Hepatology

2007, 22 (11), 1898–1903

65

The phenotypic and behavioral defects can be transferred from zinc-exposed nematodes to their progeny

Dayong Wang*, Lulu Shen, Yang Wang

Environmental  Toxicology and Pharmacology

2007, 24(3):223-230

66

Transferable properties of multi-biological toxicity caused by cobalt exposure in caenorhabditis elegans

Yang Wang,Wei Xie, and Dayong Wang*

Environmental Toxicology and Chemistry

2007,26(11):2405-2412

67

Concordant expression of proto-oncogene promyelocytic leukemia and major histocompatibility antigen HLA class I in human hepatocellular carcinoma.

M. Xia, J. Q. Zhang, Y.-Q. Shen, L. H. Xu, A. Q. Chen, F. Q. Miao & Wei Xie*

Tissue Antigens

2007, 70(4):272-282

68

Gene induction and apoptosis in human hepatocellular carcinoma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine

FAN Hong* ZHAO Zhu-jiang CHENG Yu-chao SHAN Yun-feng LU Zhu-hong ZHANG Jian-qiong XIE Wei

Chinese Medical Journal

2007,120(18):1626-1631

69

Identification of RNA binding sequences of Drosophila SR protein DX16

Liudi Yuan, Jing Zhou, Yongqi Wan, Mingkuan Sun, Yan Zhang, Fei Dou, Wei Xie*

Molecular and cellular Biochemistry

2007, 302(1-2): 119-124

70

Low-molecular-weight protein (LMP) 2/LMP7 abnormality underlies the downregulation of human leukocyte antigen class I antigen in a hepatocellular carcinoma cell line

Yu-Qing Shen, Jian-Qiong Zhang, Mei Xia, Feng-Qing Miao, Xiang-Nian Shan, Wei Xie

Journal of Gastroenterology and Hepatology

2007, 22(7):1155-1161

71

Functional analysis of the Drosophila Dnop5 gene using targeted RNA interference

Yan Zhang, Jie Ding, Yongqi Wan, Wei Xie, Liudi Yuan

International Journal of Molecular Sciences

2007,8(5):399-406

72

Induction of tumor antigen-specific cytotoxic T cell responses in naive mice by latex microspheres-based artificial antigen-presenting cell constructs

Chuanlai Shen, Jianqiong Zhang, Lingzhi Xia, Fanyan Meng, Wei Xie

Cellular Immunology

2007, 247(1):28-35

73

Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila

Xiankun Zeng, Mingkuan Sun, Li Liu, Fading Chen, Liuchan Wei, Wei Xie

FEBS Letters

2007,581(13): 2509-2516

74

Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

Wenjie Luo, Fei Dou, Anna Rodina, Sophorn Chip, Joungnam Kim, Qi Zhao, Kamalika Moulick, Julia Aguirre, Nian Wu,

Proceedings of the National Academy of Sciences

2007,104(22):9511-6

75

Silver Exposure Causes Transferable Defects of Phenotypes and Behaviors in Nematode Caenorhabditis elegans

Dayong Wang*, Peng Yang

Environmental Bioindicators

2007,2(2):89-98

76

Computational analysis of genetic loci required for amphid structure and functions and their possibly corresponding microRNAs in C. elegans

Ya-Ou HU, Yang SUN, Bo-Ping YE, Dayong Wang*

Neuroscience Bulletin

2007, 23(1):19-20

77

Hsp90 Maintains the Stability and Function of the Tau Phosphorylating Kinase GSK3β

Fei Dou*, Xingya Chang and Da Ma

International Journal of Molecular Sciences

2007, 8(1): 51-60

78

Involvement of genes required for synaptic function in aging control in C.elegans

Lu-Lu SHEN, Yang WANG, Dayong Wang*

Neuroscience Bulletin

2007, 23(1):21-29

79

LOI of IGF2 Is Associated with Esophageal Cancer and Linked to Methylation status of IGF2 DMR

Xu W, Fan H, He X, Zhang J, Xie W*

Journal of Experimental and Clinical Cancer Research   

2006, 25(4): 543-547   

80

Computational analysis of genetic loci required for synapse structure and function and their corresponding microRNAs in C. elegans

Yang Sun, Ya-Ni Zhao, Da-Yong WANG*

Neuroscience Bulletin

2006, 22(6): 339- 349

81

Learning and learning choice in the nematode Caenorhabditis elegans

Hua-Yue Ye, Bo-Ping Ye, Da-Yong Wang*

Neuroscience Bulletin

2006, 22(6):355- 360

82

Drosophila Ecp is a novel ribosome associated protein interacting with dRPL5

Daoyong Wang, Min Xu; Jiabin Liu,Yongqi Wan, Haiteng Deng, Fei Dou, Wei Xie

Biochimica et Biophysica Acta

2006, 1760 (9): 1428-1433

83

Role of aldo-keto reductases in development of prostate and breast cancer.

Junfei Jin, Paulette Krishack, and Deliang Cao*

Frontiers in Bioscience    

2006 Sep 1;11: 2767-2773

84

Screening for genetic loci affecting the active zone formation in C. elegans

Da-Yong WANG*, Yang WANG

Neuroscience Bulletin

2006,22(5): 301-304

85

Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis

Dan Liu, Ning Zhang, Jian Du, Xin Cai, Mei Zhu, Changjiang Jin, Zhen Dou, Cijian Feng, Ye Yang, Li Liu, Kunio Takeyasu, Wei Xie, Xuebiao Yao*

Biochemical and Biophysical Research Communications

2006;345(1):394-402

86

A Transgenic Marker Mouse Line Labels Cajal-Retzius Cells from the Cortical Hem and Thalamocortical axons

Chunjie Zhao, Wei Guan, Samuel J. Pleasure*

Brain Research

2006 Mar 10; 1077 (1):48-53

87

Loss of heterozygosity at 6p21.3 underlying HLA class I downregulation in gastric cancer.

X.C Wang, J.Q Zhang, Y.Q Shen, F.Q Miao, Wei Xie*

Journal of Experimental and Clinical Cancer Research   

2006;25(1):115-119

88

Structural and functional characterization of peptide-beta(2)m fused HLA-A2/MART1(27-35) complexes

Shen CL, Chang CC, Zhang JQ, Guo W, Xia LZ, Meng FY, Xie W*

Biochemical and Biophysical Research Communications

2006; 342(1):57-65

89

An Improved Recombineering Approach by Adding RecA to Red Recombination

Wang Junping, Sarow Mihail, Rientjes Jeanette, Fu Jun, Hollak Heike, Kranz Harald, Xie Wei, Stewart A. Francis, Zhang Youming*

Molecular Biotechnology

2006, 32(1):43-54