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Phenomenex:提高LC/MS分析的速度和灵敏度的色谱柱

2008.6.04

Phenomenex在ASMS2008上介绍了用于提高实验室通量的HPLC选项。海报的演讲将介绍Phenomenex的研究,关于分析生物基质中的药物化合物,和在反相LC-ESI+-MS/MS实验中,pH对于生物样品的影响。

Booth #131,用于LC/MS分析的理想色谱柱

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Jupiter 300 3u
适合于分析共流出的靠得很近的蛋白峰,Jupiter 300 3u的色谱柱比其它色谱柱给出更好的分辨率和更尖锐的峰形。这些柱子完全分辨翻译后修饰,对如细胞色素C和β -乳球蛋白等蛋白的研究非常理想。

Gemini-NX

通过第二代有机硅嫁接过程,Gemini-NX 成为一个耐用的色谱柱平台,可简化柱子的选择,对可离子化的化合物可开发稳健的方法。作为Phenomenex生产的最多样化的反相色谱柱之一,Gemini-NX 可适用于质谱-挥发性缓冲液和非挥发性缓冲液,具有高的样品装载能力,并且是市场上最耐用的、可在宽pH范围下使用的色谱柱。

Onyx 2.0 mm内径Monolithic

现在,您可以获得单片速度一样的样品通量!新的50 mm × 2.0 mm内径的规格,提供了在低压力和高效率下的快速样品通量的解决方案。

海报介绍

•分析生物基质中药物化合物的理想的样品制备和HPLC柱的选择(6月2日,11:15~3:30)

•在用反相液相-ESI+-MS/MS,分析生物源样品的碱性药物时,pH值对定量和离子抑制的影响(6月2日,11:15~3:30)

英文原文:

Improve Speed and Sensitivity for your LC/MS Analysis

Phenomenex presents HPLC options for increasing lab productivity at ASMS 2008. Visit booth #131 to see new products for LC/MS techniques and applications. Poster presentations will introduce Phenomenex research into the analysis of drug compounds in biomatrices and the effect of pH on biological samples in RP LC-ESI+-MS/MS.

Ideal Columns for LC/MS Applications – Booth #131

Jupiter® 300 3µ
Ideal for separating closely eluting proteins, Jupiter 300 3µ columns give better resolution and sharper peaks than other phases. These columns fully resolve post-translational modifications and are ideal for research on proteins such as ctytochrome C and beta-lactoglobulin.

Gemini®-NX
Through a second-generation organo-silica grafting process, Gemini-NX is a rugged column platform that simplifies column selection and enables robust method development for ionizable compounds. One of the most versatile reversed phase columns from Phenomenex, Gemini-NX excels in both MS-volatile buffers and non-volatile buffers, offers high sample loading capacity, and is one of the most durable, pH tolerant columns on the market.

Onyx™ 2.0 mm ID Monolithic
Now you can achieve sample throughput at monolithic speeds! The new 50 mm x 2.0 mm ID format offers solutions for faster sample throughput at low pressures and high efficiencies.

Poster Presentations

 • Ideal Sample Preparation and HPLC Column Choice for the Analysis of Drug Compounds in Biomatrices (M, 6/02, 11:15 - 3:30)

• Effect of pH on the Quantification and Ion Suppression of Basic Drugs in Samples of Biological Origin by RP LC-ESI+-MS/MS (M, 6/02, 11:15 - 3:30)

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