氢气能预防衰老引起的学习能力下降

　　日本这个研究工作已经被接受，尽管研究的设计不是非常出色，但研究的问题是非常引人注目的。该研究采用日本早期筛选的早衰动物SAMP8，研究结果发现，饮用含氢气水(日本Friendear公司的氢水棒)1月就可以提高动物的抗氧化能力，18周能改善动物的认知能力，保护神经细胞，是否具有延长寿命的作用就值得期待了。

　　实际上，研究抗衰老比较理想的模型可以用更简单的动物，例如线虫和果蝇。希望国内研究抗衰老方面的老师关注这个研究。是非常有意思的研究内容和方向。

　　Drinking hydrogen water ameliorated cognitive impairmentin senescence-accelerated mouse

　　Abstract

　　Hydrogen has been reported to have neuron protective effects due to its antioxidant properties, but the effects for cognitive impairment in senescence-related brain alterations and the underlying mechanism have not been characterized. In this study, we investigated the efficacies of drinking hydrogen water for prevention in spatial memory and age-related alteration of the brain using the senescence-accelerated prone mouse 8 (SAMP8), exhibiting early aging syndromes including declining abilities of learning and memory. In the water maze test, aged SAMP8 mice were impaired in place discrimination and in repeated acquisition tasks. However, treatment with hydrogen water for 30 days resulted in prevention of age-related declines in spatial memory processing abilities, associated with increased brain serotonin levels and elevation of serum antioxidant activity. In addition, drinking of hydrogen water for 18 weeks inhibited neurodegeneration in hippocampus, although marked loss of neurons were noted in control aged brain treated with regular water. Our results showed that drinking of hydrogen water on daily basis may present a novel strategy to prevent age-related cognitive disorder.

　　Key words: hydrogen water, senescence, hippocampus, oxidative stress, cognitive disorder