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科学家 Patrick O Brown（基因组学）
上一篇 / 下一篇 2010-07-22 14:15:50/ 个人分类：基因治疗实验
| 分析测试百科网y(q5N(c,m |
Patrick O Brown |
分析测试百科网7b @K\"Y^i |
| Head of Section: Genomics & Genetics > Genomics [ since 18 July 2001 ] |
部分论著与科研绩效：
http://scholar.google.com/scholar?hl=en&q=Patrick+O+Brown&btnG=Search&as_sdt=2000&as_ylo=&as_vis=0
pnas.org [HTML]MB Eisen, PT Spellman, PO Brown, … - Proceedings of the …, 1998 - National Acad Sciences
[ypKV:D/W0A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
*d |EX._#g)X q0is described that uses standard statistical algorithms to arrange genes according to similarity
.h$d.f ^,o kb0in pattern of gene expression. The output is displayed graphically, conveying the ... 分析测试百科网,[je(qRB
Cited by 9913 - Related articles - BL Direct - All 187 versions
[ypKV:D/W0A system of cluster analysis for genome-wide expression data from DNA microarray hybridization
*d |EX._#g)X q0is described that uses standard statistical algorithms to arrange genes according to similarity
.h$d.f ^,o kb0in pattern of gene expression. The output is displayed graphically, conveying the ... 分析测试百科网,[je(qRB
Cited by 9913 - Related articles - BL Direct - All 187 versions
[CITATION] Quantitative monitoring of gene expression patterns with a complementary DNA microarray
X)q5Q J-`:l4\1K0Cited by 6923 - Related articles - BL Direct - All 22 versions
cmu.edu [PDF]… , W Wilson, MR Grever, JC Byrd, D Botstein, PO Brown, … - Nature, 2000 - nature.com分析测试百科网&^/e
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Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
N%O9{`v(X0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have 分析测试百科网^;Pa s#r _X9P%_2K4J `S
prolonged survival, whereas the remainder succumb to the disease. We proposed that ... 分析测试百科网@.l,T!a&L
Cited by 5096 - Related articles - BL Direct - All 82 versions
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's
N%O9{`v(X0lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have 分析测试百科网^;Pa s#r _X9P%_2K4J `S
prolonged survival, whereas the remainder succumb to the disease. We proposed that ... 分析测试百科网@.l,T!a&L
Cited by 5096 - Related articles - BL Direct - All 82 versions
… , SX Zhu, PE Lønning, AL Børresen-Dale, PO Brown, D … - Nature, 2000 - nature.com
Q D m0tv`0Human breast tumours are diverse in their natural history and in their responsiveness to treatments 分析测试百科网 K1V+w.Xn"E-N
1 . Variation in transcriptional programs accounts for much of the biological diversity of human 分析测试百科网g)Eq!i9Z"v|
cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
*C n$\ ~+J"kt H6]0Cited by 3713 - Related articles - BL Direct - All 12 versions
Q D m0tv`0Human breast tumours are diverse in their natural history and in their responsiveness to treatments 分析测试百科网 K1V+w.Xn"E-N
1 . Variation in transcriptional programs accounts for much of the biological diversity of human 分析测试百科网g)Eq!i9Z"v|
cells and tumours. In each cell, signal transduction and regulatory systems transduce ...
*C n$\ ~+J"kt H6]0Cited by 3713 - Related articles - BL Direct - All 12 versions
ramapo.edu [PDF]JL DeRisi, VR Iyer, PO Brown - Science, 1997 - sciencemag.org分析测试百科网 t6A2B p C;jy
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
/eZ Vj_0carry out a comprehensive investigation of the temporal program of gene expression accompanying
1T R } B]Qj0the metabolic shift from fermentation to respiration. The expression profiles observed for ...
%F)w,{lh"B#M qJ0Cited by 3645 - Related articles - BL Direct - All 91 versions
DNA microarrays containing virtually every gene of Saccharomyces cerevisiae were used to
/eZ Vj_0carry out a comprehensive investigation of the temporal program of gene expression accompanying
1T R } B]Qj0the metabolic shift from fermentation to respiration. The expression profiles observed for ...
%F)w,{lh"B#M qJ0Cited by 3645 - Related articles - BL Direct - All 91 versions
molbiolcell.org [HTML]… , MB Eisen, PO Brown, D Botstein, B … - Molecular biology of …, 1998 - Am Soc Cell Biol分析测试百科网u3kI z/V'Y)o}
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance 分析测试百科网 ~k#~ ~o%W q)MS
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
!RI5{nc5BT6liJ9v3kQ0regulated have been identified using traditional methods, and it was estimated that some ... 分析测试百科网 PvB` i-C u
Cited by 3383 - Related articles - BL Direct - All 84 versions
In 1981 Hereford and coworkers discovered that yeast histone mRNAs oscillate in abundance 分析测试百科网 ~k#~ ~o%W q)MS
during the cell division cycle (Hereford et al., 1981 ). To date 104 messages that are cell cycle
!RI5{nc5BT6liJ9v3kQ0regulated have been identified using traditional methods, and it was estimated that some ... 分析测试百科网 PvB` i-C u
Cited by 3383 - Related articles - BL Direct - All 84 versions
pnas.org [HTML]… JC Matese, PO Brown, D Botstein, PE … - Proceedings of the …, 2001 - National Acad Sciences
9l:~ d8[Zm1K.v0The purpose of this study was to classify breast carcinomas based on variations in gene expression
'jKe Z!X#J0H'G0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical 分析测试百科网3rx1Jz6D Yp,B0v
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ...
i0A_1t-E!M0Cited by 2902 - Related articles - BL Direct - All 31 versions
9l:~ d8[Zm1K.v0The purpose of this study was to classify breast carcinomas based on variations in gene expression
'jKe Z!X#J0H'G0patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical 分析测试百科网3rx1Jz6D Yp,B0v
outcome. A total of 85 cDNA microarray experiments representing 78 cancers, three ...
i0A_1t-E!M0Cited by 2902 - Related articles - BL Direct - All 31 versions
molbiolcell.org [HTML]… , MB Eisen, G Storz, D Botstein, PO Brown - Molecular biology of …, 2000 - Am Soc Cell Biol分析测试百科网/yo._.f+w-G*DY
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
:o3mhg#X(T3@)Au o,q0to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
._Q:i!U N6x)X ^0levels over time for almost every yeast gene, as cells responded to temperature shocks, ... 分析测试百科网B nxSp J
Cited by 2151 - Related articles - BL Direct - All 54 versions
We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding
:o3mhg#X(T3@)Au o,q0to diverse environmental transitions. DNA microarrays were used to measure changes in transcript.
._Q:i!U N6x)X ^0levels over time for almost every yeast gene, as cells responded to temperature shocks, ... 分析测试百科网B nxSp J
Cited by 2151 - Related articles - BL Direct - All 54 versions
ctu.edu.vn [PDF]PO Brown, D Botstein - nature genetics, 1999 - ctu.edu.vn
v1D)j;Y"fJ X,d f(X0The genome project has revitalized exploration in biological research. Not long ago, it was possible 分析测试百科网.M(G/^FA ]f
for biologists to imagine that the genes that had been discovered via mutations, selections and 分析测试百科网&~ nA#^'h P
cloning schemes represented a good approximation of the total universe of genes, and ... 分析测试百科网 {,E0h%n$uw
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
v1D)j;Y"fJ X,d f(X0The genome project has revitalized exploration in biological research. Not long ago, it was possible 分析测试百科网.M(G/^FA ]f
for biologists to imagine that the genes that had been discovered via mutations, selections and 分析测试百科网&~ nA#^'h P
cloning schemes represented a good approximation of the total universe of genes, and ... 分析测试百科网 {,E0h%n$uw
Cited by 1919 - Related articles - View as HTML - BL Direct - All 82 versions
stanford.edu [PDF]J DeRisi, L Penland, PO Brown, ML Bittner, PS … - Nature …, 1996 - cmgm.stanford.edu分析测试百科网 pky0E/O
... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
s0ea)pgP/R#m5zV0Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
O\:A ac.E"O8{*|1o |0the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ...
&GMI!mY)? D0Cited by 1699 - Related articles - BL Direct - All 9 versions
... microarray to analyse gene expression patterns in human cancer Joseph DeRisi1*, Lolita
s0ea)pgP/R#m5zV0Penland2 & Patrick О ... with significantly higher expression (>10-fold) in the tumorigenic cells was
O\:A ac.E"O8{*|1o |0the human brown locus pro ... Filters were washed to a strin- gency of O.lx SSC at 42 °C for 20 ...
&GMI!mY)? D0Cited by 1699 - Related articles - BL Direct - All 9 versions
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