CEM微波合成用于Racemization的研究
发布: 2012-07-20 10:48:58来源: 培安有限公司
INTRODUCTION
One potential issue in peptide synthesis is racemization of cysteine and histidine. This is a concern for microwave peptide syntheis because of the elevated temperatures during deprotection and coupling. Studies have shown that lowering the temperature to 50 °C during the coupling of histidine and cysteine will decrease racemization.
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