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本期亮点

欢迎查阅2016年11月第75期Bruker电子期刊!我们本期的亮点是关于超高通量的药物筛选的网络讲座, 关于impact II在蛋白组-基因组学研究的最新研究文献,并关注在德国Munich的analytica会议。

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网络讲座 “12月5日非标记的超高通量的药物筛选”

新的rapifleX MALDI PharmaPulse是一款能满足药物筛选对速度,专属性和稳定性要求的质谱仪, 可用于生化分析中非标记超高通量的筛选(uHTS),非标记检测能加快和简化分析方法的开发,并能避免人为因素的影响,整体的自动化解决方案能在12mins内完成1536 HTS MALDI靶板的检测。

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网络讲座 “12月20日关于同位素精细结构”

同位素精细结构是指质谱图中的特征性质谱峰,这些特征性质谱峰是由被测物质中的元素及其同位素峰的种类和丰度差异所引起。通过不同元素的特征峰来发现新的元素, 通过决定性的原子特征信息来判断“真实分子式”,可以稳定的获得大于500000的分辨率。同位素精细结构可用于推测未知化合物的分子式,增加定量分析能力。我们来听听更多应用实例!

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最新应用文章: mAb Characterization - automated detection
of disulfide bonds by the rapifleX

FAST and simplified approach to analyze trisulfide formation in biopharmaceuticals.

New rapifleX TOF/TOF was used to automatically detect disulfide bonds in four monoclonal antibodies followed by straight-forward analysis of trisulfide formation.

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最新博客文章: No longer unknown – novel cytochrome c oxidase subunit revealed

A few years ago, researchers solved the structure of the cbb3-1 cytochrome c oxidase from Pseudomonas stutzeri. They were surprised to detect the presence of a fourth protein subunit, consisting of a single transmembrane helix, for which no proteomic or genomic information was available. In a recently published article, they have now described the identification and characterization of that previously unknown subunit…

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网络讲座回顾
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