根据欧盟指令91/414 EEC使用TSQ Quantum Ultra测定多种加工水果和蔬菜中的农药残留

前言：

　　A diet rich in fruits and vegetables is thought to reduce the risk of some types of cancer, atherosclerosis, and heart disease. However, commercially grown produce often contains high levels of pesticide residues that can lead to serious health problems when consumed. Due in large part to growing public concern over the amount of pesticide residues in foods, the European Union (EU) has enacted several directives to fix Maximum Residue Limits (MRLs) for different pesticide residues in food of plant origin. MRLs represent the maximum amount of pesticide residues that might be expected in a commodity produced under conditions of good agricultural practice and typically range between 0.01 mg/kg and 10 mg/kg1.Although MRLs are not maximum toxicological limits, care is taken to ensure that these maximum levels do not generate toxicological concerns. Thus far, MRLs have been set for approximately 250 active substances. To cover the full variety of agricultural raw commodities (approximately 260 products of plant and animal origin), MRLs must be established for more than 260,000 pesticide/commodity combinations.

仪器：

Thermo Scientific TSQ Quantum mass spectrometer

结论：

　　A multi-residue LC-ESI-MS/MS method was developed for the reliable confirmation and quantification of pesticides from different chemical classes at low ppb levels in food matrices. The method uses the Highly Selective Reaction Monitoring (H-SRM) mode of the TSQ Quantum Ultra triple quadrupole mass spectrometer to effectively reduce the background interference and improve the signal-to noise ratios. For the pesticides investigated, satisfactory precision and accuracy were achieved and Limit of Quantitation (LOQ) values of 0.010 mg/kg were established. The method can be expanded to include more pesticides and their metabolites to improve the range of pesticide residues monitored in food commodities.