400-6699-117转1000
您好,欢迎您查看分析测试百科网,请问有什么帮助您的?
分析测试百科网 认证会员,请放心拨打!
参考报价: | 1 - 4800 RMB(人民币) | 型号: | 心血管疾病PCR芯片Cardiovascular Disease PCR Array |
品牌: | 英拜生物 | 产地: | 上海 |
关注度: | 21 | 信息完整度: | |
样本: | 典型用户: | 暂无 |
400-6699-117转1000
心血管疾病PCR芯片可用于研究与心血管疾病相关的84个基因的表达情况。
The Human Cardiovascular Disease RT2 Profiler PCR Array profiles the expression of 84 genes linked to cardiac disease. Cardiovascular disease is the most important cause of morbidity and mortality in developed countries, causing twice as many deaths as cancer in the United States. Multiple genetic and environmental factors, as well as the interactions between them, increase the risk for developing major
cardiovascular diseases such as coronary artery disease (CAD), myocardial infarction (MI), and congestive heart failure (CHF), to name a few. The underlying pathogenic mechanisms for these disorders are still largely unknown, but observed gene expression changes may play a central role in the development and progression of cardiovascular disease. Microarray studies have characterized gene expression patterns in diseased and non-diseased patients leading to the identification of unique subsets of genes associated with the cardiac disease process. The genes profiled with this array play roles in molecular processes such as apoptosis, cardiac remodeling, cell cycle, cell growth, stress and immune responses, transcriptional regulation, and signal transduction. Genes encoding sarcomere structural proteins are represented as well. A set of controls present on each array enables data analysis using the ΔΔCT method of relative quantification and assessment of reverse transcription performance, genomic DNA contamination, and PCR performance. Using real-time PCR, research studies can easily and reliably analyze the expression of a focused panel of genes related to cardiovascular disease with this array.
Apoptosis: CCL2, MAOA, NDUFB5, NPPA, NPPB, NPR1, PDE3A, SNCA, THBS2, UBB, ZYX.
Cardiac Remodeling: AEBP1, ANXA4, COL11A1, COL1A1, COL3A1, DCN, DMD, F2R, FN1, GJA1, MMP13, MT1X, REN, RTN4, SERPINA3, TNNI3, TNNT2.
Cell Cycle: CCND1, CDKN1B, G0S2, RARRES1.
Cell Growth: ACE, SFRP4, SPOCK1, CTGF, PTN.
Sarcomere Structural Proteins: ACTC1, CRYAB, CRYM, MYH10, MYH6, NEBL, POSTN.
Signal Transduction: DUSP6, PDE3B, PDE7A, RASSF1, FRZB, HMGCL, HMGCR, MAPK1, MAPK8, PDE5A, SLC12A1, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3, AGTR1, NPR2, NPR3, AR, EPOR, NR3C1, NR3C2.
Stress & Immune Response: C6, CCL2, CCL11, CCL18, S100A1.
Transcriptional Regulation: CREB5, CREM, ENAH, HMGN2, KLHL3, MSI2, NFIA, NKX2-5, STAT1, TCF4.
Transporters: ATP2A2, ATP5A1.
心血管疾病PCR芯片Cardiovascular Disease PCR Array信息由上海英拜生物科技有限公司为您提供,如您想了解更多关于心血管疾病PCR芯片Cardiovascular Disease PCR Array报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途