Human T-Cell & B-Cell Activation DNA Methylation PCR Array: EAHS-531Z The Human T-Cell and B-Cell Activation EpiTect Methyl II Signature PCR Array profiles the promoter methylation status of a panel of 22 genes whose involvement in T and B lymphocyte biology has been well documented. Profiling cellular or fresh tissue DNA samples with these arrays may help correlate CpG island methylation status with the resident T cells' relative capacity for activation by external stimuli from immune and inflammatory response pathways. The results may also help provide insights into the molecular mechanisms and biological pathways behind diseases involving T cell biology such as asthma, allergies, autoimmune disorders, leukemia, and lymphoma. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the promoter methylation status of 22 different genes regulating T cell and B cell biology with this DNA methylation PCR array.
Both 96-well and 384-well ( 4 X 96 ) formats are available.

 ProductSpeciesTechnologyCat. No.T-Cell & B-Cell Activation PCR ArrayHumanGene ExpressionPAHS-053ZT-Cell & B-Cell Activation PCR ArrayMouseGene ExpressionPAMM-053ZT-Cell & B-Cell Activation PCR ArrayRatGene ExpressionPARN-053Z    

T Cell Differentiation Genes: BLM, EGR1, IL7, LCK, SOCS1, TGFB1.
T Cell Proliferation Genes: BLM, CD274, CD276, CD47, FOXP3, ICOSLG, IL12A, IL7, NCK1, RIPK2, TGFB1.
Cell Adhesion & Migration Regulators: ADA, CD47, DPP4, IL12A, NCK1, TGFB1.
MHC Protein Complex Associated Proteins: CD8A, LAG3, MICB.
Cell Cycle Regulators: BLM, IL12A, TGFB1.
Other T Cell Activation Regulators: CD7, MAP3K7, THY1.
B Cell Activation: ADA, ICOSLG, IL7, TGFB1.

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