400-6699-117转1000
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参考报价: | 500 - 5000 RMB(人民币) | 型号: | 人软脑膜周细胞 HLP |
品牌: | 英拜生物 | 产地: | 上海 |
关注度: | 4 | 信息完整度: | |
样本: | 典型用户: | 暂无 |
400-6699-117转1000
Central nervous system pericytes are perivascular cells that are closely associated with the endothelium of capillaries and other small vessels [1]. Pericytes, located near endothelial cells, communicate with other cells by extending long cytoplasmic processes which wrap around the capillaries [1, 2]. Pericytes participate in a variety of processes including angiogenesis, endothelial cell survival, regulation of capillary blood flow, and establishment and maintenance of the blood-brain barrier [3, 4]. Pericyte dysregulation has been linked to several pathological conditions such as hypertension, diabetic retinopathy, atherosclerosis, multiple sclerosis, Alzheimer’s disease, and tumor angiogenesis [2, 4]. The unique and diverse functions of pericytes make them novel candidates for cell therapy in regenerative medicine. Leptomeningeal pericytes (LP) are derived from the leptomeningeal layer surrounding the brain. Cultured human leptomeningeal pericytes (HLP) are a useful in vitro model for studying a wide variety of central nervous system diseases.
HLP are isolated from human brain. HLP are cryopreserved at passage one after purification and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HLP are characterized by immunofluorescence with antibody specific to a-smooth muscle actin and platelet derived growth factor-b (PDGF-b). HLP are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HLP are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途