小鼠气管给药套装

小鼠气溶胶肺部给药（气管内给药）套装 / 大小鼠肺部给药装置 (Liquid Aerosol Devices, MicroSprayer® Aerosolizers) 输送气溶胶提供了更好的方案，更方便、更安全、更快捷。 套装主要包括气溶胶雾化喷射头，高压注射器组成。

• 定量 QUANTIFIABLE：将定量的气溶胶给到动物肺部

• 定时 TIMED：可以在一个或多个时间点进行给药

• 有效 EFFECTIVE：气溶胶的吸收效果好，给药快速，效率高，操作方便

• 方便 CONVENIENCE：维护简单，操作方便

小鼠肺部干粉给药套装，欢迎来电咨询：
 

n  产品特点

·  快速 、 精确的直接肺 部给药 ——气溶胶 无 浪费

·  纯机械 动力，无外部空气进入

·  不需加热、 推进剂、超声波或压缩空气 等，对药物物影响

·  手持式设计的独特专利，使用非常方便

·  喷射头顶端圆滑的设计，保证安全、温和的插入气管内

·  可高温高压消毒灭菌，可重复使用

·  比其它雾化器和吸入设备提供更高浓度发药物体积或剂量

·  比传统滴注法给药提供更均匀的药物分布

n  使用方法

参考文献：

1. Li, Cheng et al. “Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.” Cell vol. 185,8 (2022): 1389-1401.e18. doi:10.1016/j.cell.2022.03.009

2. Peng, Boya et al. “Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy.” Journal of extracellular vesicles vol. 11,4 (2022): e12187. doi:10.1002/jev2.12187

3. Wu, Lan et al. “Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.” ACS applied materials & interfaces vol. 13,3 (2021): 3722-3737. doi:10.1021/acsami.0c21259

4. Tian, Xidong et al. “Pulmonary Delivery of Reactive Oxygen Species/Glutathione-Responsive Paclitaxel Dimeric Nanoparticles Improved Therapeutic Indices against Metastatic Lung Cancer.” ACS applied materials & interfaces vol. 13,48 (2021): 56858-56872. doi:10.1021/acsami.1c16351

5. Gu, Peiyu et al. “Protective function of interleukin-22 in pulmonary fibrosis.” Clinical and translational medicine vol. 11,8 (2021): e509. doi:10.1002/ctm2.509

6. Su, Ruonan et al. “Venetoclax nanomedicine alleviates acute lung injury via increasing neutrophil apoptosis.” Biomaterials science vol. 9,13 (2021): 4746-4754. doi:10.1039/d1bm00481f

7. Yang, Huilin et al. “Triptolide dose-dependently improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS mice.” Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 139 (2021): 111569. doi:10.1016/j.biopha.2021.111569

8. Wu, Yanqi et al. “SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation.” Respiratory research vol. 21,1 130. 27 May. 2020, doi:10.1186/s12931-020-01372-6

9. Han, Meishan et al. “Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis.” Frontiers in pharmacology vol. 13 882678. 25 Apr. 2022, doi:10.3389/fphar.2022.882678

10. Wu, Lan et al. “Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles.” European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V vol. 152 (2020): 108-115. doi:10.1016/j.ejpb.2020.05.004

11. Peng, Jianqing et al. “Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.” Molecules (Basel, Switzerland) vol. 27,11 3610. 4 Jun. 2022, doi:10.3390/molecules27113610

小鼠气管给药套装信息由上海玉研科学仪器有限公司为您提供，如您想了解更多关于小鼠气管给药套装报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途