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BORCS8-MEF2B 基因突变与药物因子介绍

2022.7.25

这个基因代表了跨越基因id:729991和100271849的大量读写转录本。许多通读转录本被预测为无意义介导衰变(nmd)候选,并且被认为是非编码的。一些转录本被预测能够在下游的AUG处重新启动翻译,从而从该读通位点表达至少一种心肌细胞增强因子2B(MEF2B)的亚型至少一个额外的mef2b变体和亚型可以从下游启动子表达,并在geneid:100271849上注释。[由RefSeq提供,2010年10月]
This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010]

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