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2017年度R&D 100 大奖揭晓日立、牛津、卡尔蔡司、Illumina入选

2017.11.24

　　分析测试百科网讯近日，R&D杂志宣布了2017年度R&D 100奖决赛入围者，这是第55届年度研发奖100项大奖，该奖项旨在纪念去年的100项最具创新性的技术。今年的R&D 100大奖在2017年11月17日在迪斯尼世界天鹅度假村举行的黑色领带仪式上与第三届年度R&D 100大会共同举行。研发100奖项决赛选手的独立评审团由50多位代表各个领域的研发领导者组成。

　　2017年度R&D 100奖中，日立、牛津、卡尔蔡司、Illumina等多家厂商入选。分析测试百科网精选以下进行介绍：

　　牛津

Dragonfly-高速共焦成像平台

　　Dragonfly 核心功能是多点高速，高灵敏度共聚焦成像，其采集速度比普通点扫描共聚焦技术快至20倍。另外采用高分辨，高灵敏的探测器，有效减少活细胞成像的光毒性及光漂白，同时也适合于固定样品的高分辨快速三维成像。第二种成像模式为激光照相的宽场荧光成像。这种模式特别适用于极弱荧光成像，如酵母及其他非常薄的样品，或者如钙离子成像等极高速实验。另外适用于对激光能量密度要求很高的单分子荧光定位实验，可用于单分子定位超分辨实验。这种模式得益于ZL的Borealis照明和GPU加速的反卷积。用Dragonfly做宽场成像，可以和其他模式分享相同相机和激光并且无须切换显微镜端口和滤色片转轮，达到更有效的硬件控制。第三种成像模式TIRF（全内反射荧光显微镜），这种模式适用于细胞膜及附近蛋白的动态成像及体外单分子实验。Dragonfly TIRF可以共用共聚焦显微镜、激光、成像相机和滤光片转轮等，Dragonfly TIRF系统对任意两种波长的激光激发深度做实时校准，可实现任意两种波长的同深度激发同时成像，提高不同颜色标记的定位准确性。另外，Dragonfly具有光学变倍Zoom功能，有效对成像物镜和探测器分辨率进行匹配，提高成像分辨率及灵敏度。Dragonfly激光照明部分同样具有照明Zoom功能，可用于提高激光照明密度，用于高能能量激光实验，如超分辨单分子定位及超高速快速采集成像。Dragonfly系统具有自适应光学矫正系统，保证成像质量。

　　Illumina

NovaSeq系列

　　NovaSeq仪器提供了简单易用的功能，包括自动化的蔟生成、基于卡盒的试剂以及简化的流程。利用可扩展的通量，用户能够灵活开展那些需要不同产量的测序应用。他们可从四种不同的流动槽中自由选择，并同时运行一个或两个流动槽。

　　NovaSeq 5000和6000系统的售价分别为85.0万和98.5万美元（仅适用于美国）。NovaSeq 5000可原地升级为NovaSeq 6000。这两个系统之间的差异在于它们运行的流动槽。NovaSeq 5000可运行S1和S2流动槽，而NovaSeq 6000可运行S1、S2、S3和S4四种不同的流动槽。S2格式的流动槽将最先推出，而S1、S3和S4流动槽将在2017年的晚些时候推出。根据Illumina网站上的系统参数，NovaSeq测序系统的产量范围在167 Gb至6 Tb，每次运行的reads数量在16-200亿。以S2流动槽为例，它每次运行最多可测序16个人类基因组，或132个外显子组或转录组。

　　卡尔蔡司

Celldiscoverer 7

　　Celldiscoverer 7将人性化的箱式显微镜自动化功能与传统倒置研究显微镜的高图像质量和高灵活性进行完美融合。通过这款新产品，科学家能够在更短的时间内进行2D或3D细胞培养、组织切片或小型模式生物体的研究并获取更理想的数据。

　　与其他灵活性有限的箱式显微镜相比，蔡司Celldiscoverer 7更能适应多种复杂的任务和应用。该系统可配备多种培养系统和检测系统，可以满足不同研究的多种实验需求。用户可以从众多显微镜相机中选择一款适合的用于实验，即使是要求严格的活细胞实验和快速延时拍摄也游刃有余。尤其是当系统配备了蔡司Axiocam 512 mono显微镜相机时，最高分辨率可达12MP，并拥有能够进行高性能荧光筛选的大视野。

　　蔡司Celldiscoverer 7将全新的光学设计与先进的自动校正技术相结合，能够帮助研究人员从长时间复杂的延时成像实验中获得高质量的可再现数据。它还具备一种基于硬件的自动聚焦功能，不仅能够自动寻找焦点并保持聚焦，而且可以探测出样品容器的厚度和光学属性。这个用途被用在了蔡司独特的Autocorr自动校正物镜上，为用户提供优异的图像质量。

　　日立

IE-5级效率的非晶电机

　　另有由劳伦斯伯克利国家实验室组织，中国能源部伯克利实验室和中国国家发展和改革委员会能源研究所，山东省科学院，基于最初由ESMAP开发的模型，即“城市能源快速评估工具”（TRACE）合作开发的低碳城市的标杆管理和节能工具（BEST城市）也获得了此奖。

　　由先进技术研究所（IAT）组织，中国科学技术大学光电科学与技术实验室合作开发的太阳光谱分离农业和光伏项目也获得此奖。

　　详细名单如下：

Product	Organization	Co-Developer(s)
ACE: The Ageless Aluminum Revolution	Critical Materials Institute	Eck Industries Oak Ridge National Laboratory Ames Laboratory Lawrence Livermore National Laboratory
ACMZ Cast Aluminum Alloys	Oak Ridge National Laboratory	Fiat Chrysler Automobiles US LLC Nemak U.S.A. Inc
Acoustic Gunshot Detection Technology	Pacific Northwest National Laboratory
Additively Manufactured High Temperature Polymer-Derived Ceramics	HRL Laboratories, LLC.
Additively Printed High Performance Magnets	Oak Ridge National Laboratory	Ames Laboratory Critical Materials Institute Magnet Applications Inc. Tru-Design Inc. Momentum Technologies
ANDE	ANDE, A Division of NetBio
Applied Biosystems Axiom Microbiome Array	Lawrence Livermore National Laboratory	Thermo Fisher Scientific
Battelle's Coal-to-Liquids (CTL) Process Using Biomass-Derived Solvents	Battelle
Benchmarking and Energy Saving Tool for Low-Carbon Cities (BEST Cities)	Lawrence Berkeley National Laboratory	China Energy Group of Berkeley Lab and the Energy Research Institute of China’s National Development and Reform Commission. Beta-testing: Shandong Academy of Sciences. Based on model originally developed by ESMAP known as TRACE, the Tool for the Rapid Assessment of City Energy.
BESTAI, Building Energy Simulation Technology with Artificial Intelligence	Industrial Technology Research Institute (ITRI)
Boron Suboxide, B6O, Third Hardest Material	ATS-MER, LLC
BroadSoft Team-One	BroadSoft, Inc.
ChemSEI-Linker	Industrial Technology Research Institute (ITRI)
CINmat (Microwave Annealing Technology)	National Chiao Tung University, Department of Electrophysics	Industrial Technology Research Institute, Mechanical and Mechatronics Systems Research Laboratories, National Nano Device Laboratories
Clean-Energy Electrocatalysts without Precious Metals	Los Alamos National Laboratory	Pajarito Powder, LLC
COBRA - Metabolic Fuel & Energy Sensor	MIT Lincoln Laboratory	U.S. Army Research Institute of Environmental Medicine
Compressed Sensing Cardiac Cine	Siemens Medical Solutions USA, Inc.	Siemens Healthcare, GmbH
Control System for Active Damping of Inter-Area Oscillations	Sandia National Laboratories	Montana Tech University, Bonneville Power Administration
CoolSo	Industrial Technology Research Institute (ITRI)
CrunchFlow	Lawrence Berkeley National Laboratory	University of Illinois-Champaign
CyberEpi	Industrial Technology Research Institute (ITRI)
DecaTxt-IN10DID	IN10DID, Inc.
dfnWorks	Los Alamos National Laboratory	Oak Ridge National Laboratory
Digital CoPilot	The MITRE Corporation
Distributed Solar Estimation (DiSE)	Lawrence Berkeley National Laboratory
Double Barcoded Shotgun Expression Library Sequencing (Dub-seq)	Lawrence Berkeley National Laboratory
Dow Corning TC-2022 Thermally Conductive Adhesive	The Dow Chemical Company	Delphi
Dow's Advanced FCDh Technology	The Dow Chemical Company	Snamprogetti
Dragonfly - High Speed Confocal Imaging Platform	Andor
dropletProbe Surface Sampling System for Mass Spectrometry	Oak Ridge National Laboratory	SepQuant, Inc.
EDGE Bioinformatics	Los Alamos National Laboratory	Naval Medical Research Center
ESGF	Lawrence Livermore National Laboratory	NASA, NOAA, the international laboratories in the federation, including the Australian National University’s National Computational Infrastructure (NCI), the German Climate Computing Centre (DKRZ), the Institut Pierre-Simon Laplace (IPSL), the Centre for Environmental Data Analysis (CEDA), and the Centre de Recherche Informatique de Montréal (CRIM)
Evolve 5.5 Solid-State Refrigerator	Phononic
Filler Materials for Welding and 3D Printing	Oak Ridge National Laboratory	U.S. Army Tank Automotive Research Development and Engineering Center
Friction Stir Scribe Process for Joining Dissimilar Materials	Pacific Northwest National Laboratory
Fusion FIBC / bulk bags	Dow Packaging and Specialty Plastics, a business unit of The Dow Chemical Company.	Next Generation Packaging, LLC
Geometrically Enhanced Photocathode	National Security Technologies, LLC	NanoShift LLC, Lawrence Livermore National Laboratory, General Atomics, Lawrence Berkeley National Laboratory
Ground-Based Sense-and-Avoid System (GBSAA) for Unmanned Aircraft Systems (UAS)	MIT Lincoln Laboratory	U.S. Army, SRC Inc., Kutta Technologies
HADES: The High-Fidelity Adaptive Deception & Emulation System	Sandia National Laboratories
High Power Impulse Plasma Source (HiPIPS)	Southwest Research Institute
High-performance, low-cost, flexible, single-crystal-like, GaAs-based Thin Film Transistors	TexMat LLC	TapeSolar Inc.
HP Jet Fusion 3D 4200 Printing Solution	HP, Inc.
HT-ESP Motor	Los Alamos National Laboratory	Chevron Energy Technology Company
IBM Q	IBM
IceStorm90	Coulson Ice Blast
IE5-class efficiency amorphous motor	Hitachi, Ltd.	Hitachi Industrial Equipment Systems Co.,Ltd.
INNATE Precision Packaging Resins	Dow Packaging & Specialty Plastics, a business unit of The Dow Chemical Company
IRcell	IRsweep	Pacific Northwest National Laboratory
Lake Shore Cryotronics 8600 Series VSM	Lake Shore Cryotronics, Inc.
Large-Format Additive Coating Solutions	Tru-Design, LLC	Polynt Composites, Oak Ridge National Laboratory
LCD Waste Recycling System	Industrial Technology Research Institute (ITRI)
Liquid Nails Fuze*It All Surface	PPG
MAX (Modular Agile eXoskeleton)	suitX	University of California, Berkeley
MicroPro Series Grill	Tupperware Brands Corporation
MPV-800 Multipoint Vibrometer	Polytec GmbH
Multibed Adsorption Recuperative Cooling (MARCool) System	Pacific Northwest National Laboratory	Arkema
Multiple Operating system Rotation Environment Moving Target Defense	Argonne National Laboratory
MultiWell MicroFormulator	Vanderbilt University	CN Bio Innovations
National Risk Assessment Partnership Toolset	National Energy Technology Laboratory (NETL)	Los Alamos National Laboratory, Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, Pacific Northwest National Laboratory
Non-invasive Fiber Optic Physiological Monitoring Technology (nFOPT) and Smart Care System	Huijia Health Life Technology Co., Ltd.
NovaSeq Series	Illumina
Oleo Sponge	Argonne National Laboratory
PHM, Prognostic and Health Management Software in Semiconductors	Industrial Technology Research Institute (ITRI)
PipeAssess PI	Battelle
PolarDry Electrostatic Spray Dryer	Fluid Air	Spraying Systems Co.
Polarimetric Co-location Layering	MIT Lincoln Laboratory
Power and Thermal-aware Electronic System Level Platform, PT-ESL	Industrial Technology Research Institute (ITRI)
Premium Compact Process Primer	PPG
PRESymptomatic AGent Exposure Detection (PRESAGED)	MIT Lincoln Laboratory	U.S. Army Medical Research Institute of Infectious Diseases
Prime 95B Scientific CMOS Camera	Photometrics
Pulse-to-Pulse Phase Diversity Processing for Interference Suppression and Range Disambiguation	MIT Lincoln Laboratory
Q-Carbon and Diamond Related Products	Q-Carbon, LLC	North Carolina State University
Radiation Field Training Simulator (RaFTS)	Lawrence Livermore National Laboratory
Radiation Pressure Power Meter	Scientech Inc.	National Institute of Standards and Technology
Resin Transfer Molding (RTM) 370 Resin for High-Temperature Applications	NASA Glenn Research Center
Ropaque NT-2900 Opaque Polymer for BLUE 4EST Thermal Paper	The Dow Chemical Company	The Koehler Paper Group
Rust-Oleum META Prime	Rust-Oleum
Safe2Ditch: An Autonomous Emergency Flight Management System That Finds Safe and Clear Crash Sites for Unmanned Aerial Vehicles in Emergency Situations	NASA Langley Research Center
Safeguard	NASA Langley Research Center
SAFIRE - Safe Impact Resistant Electrolyte	Oak Ridge National Laboratory	University of Rochester
SensoSCAN	Sensogram Technologies Inc
SerialTap	Pacific Northwest National Laboratory
Shape Memory Alloy Rock Splitters (SMARS)	NASA Glenn Research Center	Jacobs Engineering
SHIELDS Space Weather Platform	Los Alamos National Laboratory	University of Michigan
Smart LEak Detection (SLED) System	Southwest Research Institute
SolidSense Gas Analyzer	Sandia National Laboratories	University of New Mexico
Structures for Lossless Ion Manipulations (SLIM)	Pacific Northwest National Laboratory
Sun Light Spectrum Separation for Agriculture & Photovoltaic	Institute of Advanced Technology (IAT)	Optoelectroic Science and Technology Laboratory, University of Science and Technology of China (USTC)
Syl-Off EM Silicone Emulsion	Dow Corning Europe S.A.
TEAMM- Electrafil PPS 3D; Electrafil PPSU 3D	Techmer PM	BASF, Oak Ridge National Laboratory
The Lightning Pack (Electricity Generating Backpack)	Lightning Packs, LLC
The Microgrid Design Toolkit (MDT)	Sandia National Laboratories
Ultra-Wide-Bandgap Power Electronics	Sandia National Laboratories
Ultrathin multifunctional hybrid coatings and processes	General Motors	Forge Nano (Formerly PneumatiCoat Technologies)
VORA Zzz Additive Technology for Ultra-High Airflow PU Memory Foam	The Dow Chemical Company
Wearable Detection Device (WDD)	Radiation Detection Technologies, Inc.	SMART Laboratory (Kansas State University), Electronics Design Laboratory (Kansas State University), Alion Science and Technology Corp., Defense Threat Reduction Agency (DTRA)
Wide-area Infrared System for Persistent Surveillance (WISP)	MIT Lincoln Laboratory
WikiEpiCast	Los Alamos National Laboratory
ZEISS Celldiscoverer 7	Carl Zeiss Microscopy GmbH
Zirconia Electrochemical Hydrogen Safety Sensor	Los Alamos National Laboratory	Lawrence Livermore National Laboratory, Hydrogen Frontier, Inc.