TUBG1基因编码的功能和结构描述
这个基因编码微管蛋白超家族的一个成员。编码的蛋白质定位于中心体,在中心体与微管结合,形成伽玛-微管蛋白环复合物。蛋白质介导微管成核,是微管形成和细胞周期进展所必需的。在7号染色体上发现了这个基因的假基因。
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
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