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实体肿瘤检测XRCC2基因介绍

2022.9.06

该基因编码reca/rad51相关蛋白家族的一个成员,参与同源重组以维持染色体稳定性和修复dna损伤。该基因通过同源重组参与dna双链断裂的修复,并在功能上与中国仓鼠irs1互补,irs1是一种修复缺陷突变体,对多种不同的dna损伤剂表现出超敏反应。

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [

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