ERF基因突变与药物因子介绍
ets2是一种转录因子和原癌基因,参与端粒酶的发育、凋亡和调控。该基因编码的蛋白与ets2启动子结合,是ets2转录的一个强抑制因子。已经发现了编码两种不同亚型的转录变体。[由RefSeq提供,2015年8月]
ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
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