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PPP1R15A基因编码的功能和结构描述

2022.8.22

这个基因是一组基因的一员,在紧张的生长停滞状态和用DNA破坏剂治疗后,这些基因的转录水平会增加。无论p53的状态如何,电离辐射对该基因的诱都发生在某些细胞系中,其蛋白反应与电离辐射后细胞凋亡有关。

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

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