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VEGFC基因编码的功能和结构描述

2022.8.23

该基因编码的蛋白是血小板衍生生长因子/血管内皮生长因子(pdgf/vegf)家族的成员。编码蛋白促进血管生成和内皮细胞生长,并能影响血管的通透性。前蛋白进一步被切割成一个完全加工的形式,可以结合和激活vegfr-2和vegfr-3受体。

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors.

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