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FOXA1基因编码功能及结构描述

2022.8.09

这个基因编码dna结合蛋白叉头类的一个成员。这些肝细胞核因子是肝特异性转录物如白蛋白和甲状腺素的转录激活因子,它们也与染色质相互作用。相似的家族成员在小鼠的代谢调节和胰腺、肝脏的分化中也有作用。[由RefSeq提供,2008年7月]

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008]

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