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SNAI1基因编码的功能和结构描述

2022.8.22

果蝇胚胎蛋白蜗牛是一种锌指转录抑制因子,下调中胚层外胚层基因的表达。该基因编码的核蛋白在结构上与果蝇蜗牛蛋白相似,也被认为是发育中胚胎中胚层形成的关键。在2号染色体上至少发现了两个类似的加工假基因变体。

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. 

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