脂肪酸代谢PCR芯片可用于研究参与脂肪酸代谢的调控和酶通路的84个关键基因的表达。细胞，尤其是骨骼肌和脂肪组织中的细胞，主要以三酸甘油酯的形式储存能量，在需要时，将其降解为丙三醇和脂肪酸，活化并运输到线粒体中。â-氧化过程代谢这些活化的脂肪酸，产生乙酰辅酶A，这也是三羧酸循环和生酮作用必要的起始代谢步骤。在静息状态下，细胞通过重新合成脂肪酸储存多余能量，此过程受到激素的严格调控。参与脂肪酸代谢的基因（如CRAT）的表达发生变化，常常与代谢综合症和胰岛素抵抗有关。而这两种病征是多种疾病的风险因子，包括糖尿病、肥胖症、心血管疾病等广泛存在的健康问题。通过实时定量PCR的方法，研究者即能够利用该芯片简单可靠地同时检测脂肪酸代谢相关的基因表达。
 

Product	Species	Technology	Cat. No.
Fatty Acid Metabolism PCR Array	Human	Gene Expression	PAHS-007Z
Fatty Acid Metabolism PCR Array	Mouse	Gene Expression	PAMM-007Z
Fatty Acid Metabolism PCR Array	Rat	Gene Expression	PARN-007Z
Fatty Acid Metabolism PCR Array	Chicken	Gene Expression	PAGG-007Z

Fatty Acid Metabolism: Acetyl-CoA Transferases: ACAA1, ACAA2, ACAT1, ACAT2. Acyl-CoA Dehydrogenases: ACAD9, ACAD10, ACAD11, ACADL, ACADM, ACADS, ACADSB, ACADVL, EHHADH, GCDH. Acyl-CoA Oxidases: ACOX1, ACOX2, ACOX3. Acyl-CoA Synthetases: ACSBG1, ACSBG2, ACSL1, ACSL3, ACSL4, ACSL5, ACSL6, ACSM3, ACSM4, ACSM5. Acyl-CoA Thioesterases: ACOT1, ACOT6, ACOT7, ACOT8, ACOT9, ACOT12. Carnitine Transferases: CPT1A, CPT1B, CPT1C, CPT2, CRAT, CROT. Others: ALDH2, DECR1, DECR2, ECHS1, ECI2 (PECI), HADHA, MCEE, MUT, PECR, PPA1. Fatty Acid Transport: CPT1A, CPT1B, CPT1C, CPT2, CRAT, CROT, FABP1, FABP2, FABP3, FABP4, FABP5, FABP6, FABP7, SLC27A1, SLC27A2, SLC27A3, SLC27A4, SLC27A5, SLC27A6. Fatty Acid Biosynthesis Regulation: FASN, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKACA, PRKACB, PRKAG1, PRKAG2, PRKAG3. Ketogenesis & Ketone Body Metabolism: BDH1, BDH2, HMGCL, HMGCS1, HMGCS2, OXCT2. Triacylglycerol Metabolism: GK, GK2, GPD1, GPD2, LIPE, LPL.