转录本基因功能研究:崭新的基因功能研究机会
研究案例-MAT2B:
Aliases | Descriptions |
MAT-II 2 | DTDP-4-keto-6-deoxy-D-glucose 4-reductase 2, 3 |
MATIIbeta 1, 2 | MAT II beta 3 |
MGC12237 2 | Methionine adenosyltransferase 2 beta subunit 3 |
Nbla02999 2 | Methionine adenosyltransferase II beta 3 |
TGR 2, 3 | beta regulatory subunit of methionine adenosyltransferase 2 |
Summary:
The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]
Function:
Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2(MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition
REFSEQ proteins (2 alternative transcripts):
NP_037415.1
NP_877725.1
转录本研究成果:IF=12.4
转录本现象在自然界普遍存在,但是,至今没有很好的方法进行深入的研究,直到RNAI和回复实验相结合:
可以实现的转录本研究的候选基因请致电吉凯基因查询。
RNAI干扰回复实验技术说明:
RNAI干扰回复实验技术说明:
Blastp:
Blast结论:
MAT2B的两个转录本仅在一端有差异:
转录本基因功能研究: 崭新的基因功能研究机会价格
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