Product Species Technology Cat. No. Breast Cancer PCR Array Human Gene Expression PAHS-131Z Breast Cancer PCR Array Mouse Gene Expression PAMM-131Z Breast Cancer PCR Array Rat Gene Expression PARN-131Z

 Human Breast Cancer PCR Array

乳腺癌RT² Profiler™ PCR Array可以同时测定84个与乳腺癌有关的关键基因。其中包括与乳腺癌直接相关的基因，信号传导相关的基因。其中还包括用作疾病标记物的在乳腺癌中表达的基因。一些与肿瘤化疗相关的基因也包括其中。利用实时定量PCR，你可以方便并且可信地对与乳腺癌相关的基因进行同时检测。

Tumor Classification Markers:
Luminal A-C: ESR1 (ERa), FOXA1, GATA3, KRT8, KRT18, SLC39A6, TFF3, XBP1.
HER2-like: ERBB2 (HER2), GRB7.
Basal-like / Triple Negative: BIRC5, EGFR, KRT5, NOTCH1.
Metastasis to Lung: ID1, MMP2 (Gelatinase A), PTGS2 (COX2).
Signal Transduction:
Steroid Receptor-Mediated: AR, BRCA1, CCNE1, CTNNB1, ESR1 (ERa), ESR2 (ERß), IGF1, KRT19, PGR, RB1.
Hedgehog: BCL2, CCND1, GLI1, SNAI2.
Glucocorticoid: IGFBP3, NME1 (NM23A), NR3C1 (GRL).
Classical WNT: APC, CCND1, CTNNB1, SFRP1.
PI3K/AKT: AKT1, ERBB2 (HER2), IGF1, IGF1R, PTEN.
NOTCH: BIRC5, NOTCH1.
MAPK: MAPK1 (ERK2), MAPK3 (ERK1), MAPK8 (JNK1), TP73.
Epithelial to Mesenchymal Transition: CTNNB1, NOTCH1, SRC, TGFB1, TWIST1.
Angiogenesis: CDH13, CTNNB1, EGF, ERBB2 (HER2), ID1, IL6, JUN, NOTCH1, PLAU (uPA), PTEN, SERPINE1(PAI-1), SLIT2, THBS1, VEGFA.
Adhesion: ADAM23, APC, BCL2, CDH1 (E-Cadherin), CDH13, CDKN2A (p16INK4), CSF1 (MCSF), CTNNB1,EGFR, ERBB2 (HER2), PTEN, TGFB1, THBS1.
Proteolysis: ADAM23, CST6, CTSD, MMP2 (Gelatinase A), MMP9 (Gelatinase B), PLAU (uPA), PYCARD (ASC).
Apoptosis: AKT1, APC, BAD, BCL2, CDH1 (E-CADHERIN), CDH1 (E-CADHERIN)3, CDKN1A (P21CIP1/WAF1),CDKN2A (p16INK4), GSTP1, IGF1, IL6, JUN, MUC1, NME1 (NM23A), RARB, SFN (14-3-3s), SFRP1, TP53, TP73,TWIST1.
Cell Cycle: APC, BCL2, CCNA1, CCND1, CCND2, CCNE1, CDK2, CDKN1A (p21CIP1/WAF1), CDKN1C(p57KIP2), CDKN2A (p16INK4), JUN, MKI67, MYC, PTEN, RASSF1, RB1, SFN (14-3-3s), TP53.
DNA Damage: APC, ATM, BRCA1, BRCA2, CCND1, CDKN1A (p21CIP1/WAF1), MAPK1 (ERK2), MGMT (AGT),MLH1, SFN (14-3-3s), TP53, TP73.
Xenobiotic Transport: ABCB1 (MDR-1), ABCG2 (BCRP).
Transcription Factors: AR, CTNNB1, ESR1 (ERa), ESR2 (ERß), FOXA1, GATA3, HIC1, JUN, MYC, NOTCH1,
NR3C1 (GRL), PGR, PRDM2 (RIZ1), RARB, RB1, TP53, TP73, XBP1.

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乳腺癌基因芯片(Breast cancer PCR Array)价格

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