ASTM E2524-08(2013)
分析纳米粒子溶血性能的标准试验方法

Standard Test Method for Analysis of Hemolytic Properties of Nanoparticles


标准号
ASTM E2524-08(2013)
发布
2008年
发布单位
美国材料与试验协会
替代标准
ASTM E2524-22
当前最新
ASTM E2524-22
 
 
引用标准
ASTM F1877 ASTM F1903 ASTM F748 ASTM F756 ISO 10993-4
适用范围

5.1 This test method is one of a series of tests listed in Practice F748 and ISO 10993-4 to assess the biocompatibility of materials contacting blood in medical applications.

5.2 This test method is similar to Practice F756 but modified to accommodate nanoparticulate materials.

TABLE 1 Calibration Standards

Level

Nominal Conc.,
mg/mL

Preparation Procedure

Cal 1

0.8

2 mL of stock solution

Cal 2

0.4

1 mL of Cal1 + 1 mL of CMH reagent

Cal 3

0.2

1 mL of Cal2 + 1 mL of CMH reagent

Cal 4

0.1

1 mL of Cal3 + 1 mL of CMH reagent

Cal 5

0.05

1 mL of Cal4 + 1 mL of CMH reagent

Cal 6

0.025

1 mL of Cal5 + 1 mL of CMH reagent