商用质谱的发展史

Mass Spectrometry Commercial Development Timeline

1957
First Knudsen cell/mass spectrometer system for high temperature thermodynamics research/ NUCLIDE ASSOCIATES of State College, PA.

1958
First GC/MS assembled by Roland Gohlke and Fred McLafferty at DOW CHEMICAL RESEARCH LABORATORY in Midland, MI, using a Model 12-101 Time-of-Flight mass spectrometer by Bendix Corp. Direct coupling of GC effluent using a needle valve.

1959
Multiple ion monitoring invented on TOF mass spectrometer by Donald Damoth of BENDIX RESEARCH LAB

Solids inlet probe on mass spectrometer invented by Donald Damoth of BENDIX RESEARCH LAB. Used for first MS confirmation of molecular weight of cholesterol for Dr. Djerassi of Wayne State University.

1960
First mass spectrometer with solids injection probe sold to UNITED STATES PUBLIC HEALTH SERVICE LABS in Cincinnati, OH. Used by Dr. Richard Kupel to study the decomposition of Teflon.

1962
Total ion monitoring invented by Donald Damoth and Roland Gohlke for GC/MS.

1963
First commercial Quadrupole mass spectrometer sold by ELECTRONICS ASSOCIATES, INC. to NASA as residual gas analyzer for space chamber research.

First Magnetic Sector mass spectrometer sold by HITACHI for GC/MS research.

1964
GC/MS designed and built by Ragnar Ryhage of the KAROLINSKA INSTITUTE in Stockholm, Sweden.

1965
First pre-packaged Magnetic Sector mass spectrometer with Helium enrichment jet separator by Ragnar Ryhage of the Karolinska Institute, sold by LKB INSTRUMENTS.

1967
Robert Finnigan leaves EAI to start FINNIGAN INSTRUMENTS and commercializes Quadrupole GC/MS.

PERKIN ELMER introduces first magnetic double focusing GC/MS, Model 270.