Next level imaging Mass Spectrometry: Single cells in focus with SpatialOMx

主讲人 Ron Heeren ,2020布鲁克MALDI和4D-蛋白质组学新技术研讨会 未经授权,禁止转载



2020布鲁克MALDI和4D-蛋白质组学新技术研讨会 的其他讲座视频
2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

What‘s New with Bruker

主讲人: Rohan Thakur,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Clinical Proteomics in interesting times

主讲人: Roman Fischer,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Introducing the timsTOF fleX with MALDI-2

主讲人: Michael L. Easterling,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

diaPASEF webinar_Apr 2020

主讲人: Ben Collins,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Hannes Rӧst - ASBMB 2019 Presentation

主讲人: Hannes Rӧst,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Metabolomics Breakfast #3

主讲人: Di Poto,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Metabolomics Breakfast #2

主讲人: Vasilopoulou,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

eXceed Imaging #2

主讲人: Heijs,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

SpatialOMXBreakfast#2

主讲人: Dreisewerd&Soltwisch,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

ProteomicsBreakfast#3Park

主讲人: ProteomicsBreakfast#3Park,

2020布鲁克MALDI和4D-蛋白质组学新技术研讨会

Elizabeth Vanderbilt

主讲人: ,

2020年6月1日美国马萨诸塞州比勒里卡 --在ASMS 2020网络大会上发布了世界上第一个商用MALDI后电离(PI)离子源MALDI-2。现在MALDI-2 离子源作为选配项可用于timsTOF fleX™ ESI / MALDI质谱仪上。全新的MALDI-2离子源可将小分子和脂质分析的灵敏度提高一到两个数量级,从而进一步扩大MALDI质谱与基于MALDI技术的质谱成像应用范围。

此外,布鲁克还推出了基于TIMS / PASEF的4D-蛋白质组学新方法,包括全新的PRM方法prm-PASEF®、短梯度DIA方法dia-PASEF®、4D数据采集与分析MOMA(Mobility Offset Mass Aligned)以及基于GPU实时数据搜索引擎的“Run & Done”数据分析方法。4D-蛋白质组学每次样本分析能产生成千上万条多肽的精确CCS (碰撞横截面积)值,这些新的方法都是基于对这些精确的CCS值的大规模并实时利用,从而大大提高蛋白、多肽和PTMs鉴定的深度和可靠性,除此之外,CCS值创新性的使用,也为LFQ分析带来了超稳定和超高灵敏度的性能,并在timsTOF Pro这一极其稳定的质谱平台上实现了真正高通量4D-蛋白质组学、4D-脂质组学和4D-代谢组学。

本次讲座将详细介绍2020年ASMS期间布鲁克发布的最新质谱技术及前沿应用。

Key Speakers:

What‘s New with Bruker25min1:30-1:55pm

Rohan Thakur, PhD, Managing Director and Executive Vice President, Life Sciences Mass Spectrometry, Bruker Daltonik GmbH, Bremen, Germany

The Synergies of Mass Spectrometry and Informatics25min1:55-2:20pm

Prof. John Yates, PhD, The Scripps Research Institute, Molecular Medicine, La Jolla, CA, USA

Next level imaging Mass Spectrometry: Single cells in focus with SpatialOMx25min2:20-2:45pm

Prof. Ron Heeren, PhD, Maastricht University, Division Head Imaging MS, Maastricht, Netherlands

Featured Speakers Proteomics/BioPharma Session

Advances in 4D-Proteomics with the timsTOF Pro: PASEF, dia-PASEF, prm-PASEF, MOMA, and RTMS30min2:45-3:15pm

Gary H. Kruppa, PhD, Vice President Proteomics, Bruker Daltonics, Billerica, MA, USA

Clinical Proteomics in interesting times30min3:15-3:45pm

Roman Fischer, PhD, Associate Professor and Head of Discovery Proteomics Facility, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Developing PRM on the timsTOF Pro for biomarker studies in cerebrospinal fluid15min3:45-4:00pm

Jarrod Marto, PhD, Associate Professor Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

Human leukocyte antigen II immunopeptidomics in dendritic cells in response to immune-complexes of TNF with anti-TNF biotherapeutics20min4:00-4:20pm

Andrea Casasola-LaMacchia, PhD, Postdoctoral Fellow, Immunogenicity, Biomedicine Design and Hendrik Neubert, PhD, Senior Director Biomeasures, Dynamics and Metabolism Department, Pfizer, New York, NY, USA

Featured Speakers spatialOMx/Imaging Session

Introducing the timsTOF fleX with MALDI-2 (20min)4:20-4:40pm

Michael L. Easterling, PhD, Global MS Imaging Director, Bruker Daltonics, Billerica, MA, USA

High-speed MALDI-2 on a timsTOF fleX: An overview of applications20min4:40-5:00pm

Dr.Bram Heijs, Head Mass Spectrometry Imaging Group, Center for Proteomics & Metabolomics, Leiden University Medical Center, Leiden, The Netherlands

Application of SpatialOMx for the discovery of biomarkers of hepatocellular carcinoma30min5:00-5:30pm

Prof. Anand Mehta, PhD, Cell and Molecular Pharmacology and Experimental Therapeutics, College of Medicine, Medical University of South Carolina, Charleston, SC, USA

Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS): A Multiplexed Microarray Platform for Targeted Proteomics (20min5:30-5:50pm

Ghaith Hamza, PhD, Proteomics Specialist , Astra Zeneca, BioPharmaceuticals R&D, Discovery Science, MA, USA


仪器频道Webinar中提到的产品
Bruker timsTOF fleX MALDI-2分析系统
Bruker timsTOF fleX MALDI-2分析系统

询价 申请演示

timsTOF fleX空间定位组学捕集离子淌度质谱(Q-TOF)
timsTOF fleX空间定位组学捕集离子淌度质谱(Q-TOF)

询价 申请演示

布鲁克 timsTOF™ Pro 捕集离子淌度质谱
布鲁克 timsTOF™ Pro 捕集离子淌度质谱

询价 申请演示

我要参会

直播分析测试百科网

QQ群号:254280557

更多 微信群
Antpedia 生物医药群
Antpedia 生物医药群

217/500 加入群

加入群
Antpedia 材料化工群

103/500

加入群
Antpedia 环境能源群

75/500

加入群
Antpedia 食品安全群

82/500

加入群
Antpedia 前处理分析群

58/500

加入群
Antpedia 质谱群

343/500

Copyright ©2007-2024 ANTPedia, All Rights Reserved

京ICP备07018254号 京公网安备1101085018 电信与信息服务业务经营许可证:京ICP证110310号