您现在所在的位置:首页 >> 仪器导购 >> 液质联用仪>> timsTOF 离子淌度-QTOF质谱仪

timsTOF 离子淌度-QTOF质谱仪

tel: 010-85170888 2005

布鲁克液质联用仪, 最大离子淌度分辨率可达200,专利阱捕获的离子淌度TIMS

阱捕获的离子淌度TIMS

离子淌度分辨率:200

QTOF分辨率:50,000


Raffinose, Melezitose and Maltotriose have the same elemental composition C18H32O16, but differ in structure:

A. timsTOF separates the isomeric trisaccharides with ion mobility resolution of 80.

B. imeX technology allows adjusting ion mobility resolution which is increased to 120 in this acquisition.

C. imeX ultra mode allows baseline separation of the trisaccharides with ion mobility resolution of 185.

1466714098902541.jpg


Technical Insights

Trapped Ion Mobility Spectrometry (TIMS) leverages the drag of an electrical field in the TIMS tunnel, while a gas flow is pushing ions forward. At the position where these opposing forces balance out for an individual ion, it is held in place according to the charge state and collisional cross sections (CCS). The larger the collisional cross section of an ion, the stronger the force that it experiences from the gas flow. When ramping down the electrical field ions are selectively released and thus separated according to size and shape.

Dive into the details of TIMS

imeXTM technology

imeX Technology allows adjusting the ion mobility resolution of timsTOF during data acquisition. In imeX survey mode, ions along the full mass range are analyzed to generate an overview spectrum that is resolved by ion mobility. Use the different imeX modes to magnify a specific mobility range for more accurate analysis of collisional cross sections or resolve overlapping ions with ultra-high mobility resolution, respectively.

Parallel accumulation

Ion mobility separation and the controlled release of ions from the TIMS tunnel occur in the second section of the TIMS analyzer. This process requires time (microseconds) during which no further ions can be collected in this section of the TIMS tunnel. With parallel accumulation, new ions are not discarded but instead collected in the first section of the TIMS analyzer, minimizing loss of analytes. Once the second section is free, the collected ions advance and undergo separation. Parallel accumulation maximizes the instrument duty cycle to close to 100%.

Instrument geometry

In timsTOF, ion mobility separation takes place at the beginning of the ion path. Only then, the separated ions enter the quadrupole for precursor isolation. As a result, precursor ions for fragmentation have undergone selection by both ion mobility and the quadrupole, which generates very clean MS/MS spectra. Furthermore, this geometry ensures that MS and MS/MS information remains correlated and are accurately assigned in displayed heatmaps.

Open data format

timsTOF introduces the novel TIMS Data Format (*.tdf) using the open source SQLite technology. The standardized SQL data access provides an efficient and flexible way to retrieve all relevant information and therefore greatly enhances transparency of data analysis and processing with unparalleled performance. Hence, the approach enables you to create software tools tailored to your specific research questions.


Open Data Format Illustration
Figure 1. Efficient and flexibile data acess based on SQLite technology and integrated *.tdf





timsTOF 离子淌度-QTOF质谱仪

参考成交价格: 60万元[美元]

询底价

售后服务

我会维修/培训/做方法

如果您是一名工程师或者专业维修科学 仪器的服务商,都可参与登记,我们的平台 会为您的服务精确的定位并展示。

1该产品的品牌知名度如何?
2你对该产品的使用感受如何?
3该产品的性价比如何?
4该产品的售务如何?
查看
在线咨询

在线咨询时间:

周一至周五

早9:00 - 晚17:30

若您在周六周日咨询,请直接留言您所咨询的产品名称+联系人+电话