ACS InfectiousDiseases 将成为第一份强调化学及其在这一多学科和合作研究领域中的作用的期刊。该杂志将涵盖各种主题，包括但不限于： * 发现和开发新的抗菌药物——通过基于目标或表型的方法以及与抗菌药物产生协同作用的化合物来识别。 * 药物靶点或途径的表征和验证——使用单一靶点和全基因组敲低和敲除、生化研究、结构生物学、新技术来促进潜在药物靶点的表征和优先排序。 * 耐药机制——增进我们对耐药性理解的基础研究；防止抵抗的策略。 * 作用机制——利用遗传、代谢组学以及基于活性和亲和力的蛋白质分析来阐明临床和实验抗菌药物的作用机制。 * 宿主-病原体相互作用——用于研究宿主-病原体相互作用、宿主和病原体的细胞生物化学以及病原体与宿主微生物群的分子相互作用的工具。 * 传染病小分子疫苗佐剂。 * 病毒和细菌生物化学和分子生物学。

ACS Infectious Diseases will be the first journal to highlight chemistry and its role in this multidisciplinary and collaborative research area. The journal will cover a diverse array of topics including, but not limited to: * Discovery and development of new antimicrobial agents — identified through target- or phenotypic-based approaches as well as compounds that induce synergy with antimicrobials. * Characterization and validation of drug target or pathways — use of single target and genome-wide knockdown and knockouts, biochemical studies, structural biology, new technologies to facilitate characterization and prioritization of potential drug targets. * Mechanism of drug resistance — fundamental research that advances our understanding of resistance; strategies to prevent resistance. * Mechanisms of action — use of genetic, metabolomic, and activity- and affinity-based protein profiling to elucidate the mechanism of action of clinical and experimental antimicrobial agents. * Host-pathogen interactions — tools for studying host-pathogen interactions, cellular biochemistry of hosts and pathogens, and molecular interactions of pathogens with host microbiota. * Small molecule vaccine adjuvants for infectious disease. * Viral and bacterial biochemistry and molecular biology.