植物发育生物学研究室
400-6699-117转1000
张大兵，教育部长江学者奖励计划特聘教授和国家百千万人才工程、国家杰出青年基金获得者、上海市优秀学科带头人、上海科技启明星、上海市曙光学者、教育部新世纪优秀人才等。
1998年2月于中科院上海植物生理生态研究所获博士学位。 中国植物学会第十三届理事会 植物生理及分子生物学专业委员会委员；上海市生物化学与分子生物学会理事；上海市科学技术委员会技术预见专家；《Journal of Integrative Plant Biology》、《Journal of Plant Physiology》、《Journal of Genetics & Genomics》、《Journal of Food Safety & Quality》等期刊编委；上海交通大学Bio-X中心伦理委员会委员。
张大兵教授研究组主要开展水稻遗传学、花器官和花药形成分子基础以及分子辅助育种等研究工作。在控制水稻花和花序分生组织控制、花粉形成功能基因克隆等方面开展了系统地工作，主持了国家杰出青年基金项目、国家自然科学基金重点等 国家和省、部委的研究课题，分离了控制水稻重要农艺性状关键基因FON4（Flower Organ Number 4）、TDR(Tapetum Degradation Retardation)、REP1(Retarded Palea1)、CYP704B2和CSA(Carbon Starved Anther)等 。近年来以通讯作者身份在Plant Cell等期刊上发表论文80多篇。作为第一完成人获得上海市科技进步奖一项。 组织申报教育部“生物技术”特色专业、“生物化学与分子生物学“国家以及上海市重点学科等。
代表性论文如下：
Li H, Yuan Z, Vizcay-Barrena G, Yang CY, Liang WQ, Zong J, Wilson Z, Zhang DB*. PERSISTENT TAPETAL CELL 1 (PTC1) encodes a PHD-finger protein that is required for tapetal cell death and pollen development in rice. Plant Physioloy. 2011,10.1104/pp.111.175760. (*通讯作者).
Li HF, Liang WQ, Yin CS, Zhu L, and Zhang DB*. Genetic interaction of OsMADS3, DROOPING LEAF and OsMADS13 in specifying rice floral organs identities and meristem determinacy. Plant Physioloy. 2011, 10.1104/pp.111.172080. (*通讯作者).
Wang CM and Zhang DB*. A novel compression tool for efficient storage of genome resequencing data. Nucleic Acids Research, 10 (2011), 1093/nar/gkr009. (*通讯作者).
Hu LF, Liang WQ, Yin CS, Cui X, Zong J, Wang X, Hu JP and Zhang DB*. Rice MADS3 regulates ROS homeostasis during late anther development. The Plant Cell, 23(2)(2011), 515-533. (*通讯作者).
Zhang Z, Zhang Y, Tan HX,Wang Y, Li G, Liang WQ, Yuan Z, Hu JP, Ren HY, and Zhang DB*. RICE MORPHOLOGY DETERMINANT encodes the type II formin FH5 and regulates rice morphogenesis. The Plant Cell, 23(2) (2011), 681–700. (*通讯作者).
Xu J, Yang CY, Yuan Z, Zhang DS, Gondwe MY, Ding ZW, Liang WQ, Zhang DB*, and Wilson ZA. Regulatory network of ABORTED MICROSPORES (AMS) required for postmeiotic male reproductive development in Arabidopsis thaliana. The Plant Cell, 22(1) (2010), 91-107. (*通讯作者).
Wang CM, Xu J, Zhang DS, Wilson ZA, and Zhang DB*. An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data. BMC Bioinformatics, 11 (2010), 81. (*通讯作者).
Li H, Pinot F, Sauveplane V, Werck-Reichhart D, Diehl P, Schreiber L, Franke R, Zhang P, Chen L, Gao YW, Liang WQ, and Zhang DB*. CYP704B2 catalyzing the ω-hydroxylation of fatty acids is required for anther cutin biosynthesis and pollen exine formation in rice. The Plant Cell, 22(1) (2010), 173-190. (*通讯作者).
Li HF, Liang WQ, Jia RD, Yin CS, Zong J, Kong HZ, and Zhang DB*. The AGL6-like gene OsMADS6 regulates floral organ and meristem identities in rice. Cell Research, 20(3) (2010), 299-313. (*通讯作者).
Zhang H, Liang WQ, Yang XJ, Luo X, Jiang N, Ma H, and Zhang DB*. Carbon Starved Anther (CSA) encoding a MYB domain protein regulates sugar partitioning required for rice pollen development. The Plant Cell, 22(3) (2010), 672-689. (*通讯作者).
Zhang DS, Liang WQ, Yin C, Zong J, Gu F, and Zhang DB*. OsC6, encoding a lipid transfer protein (LTP), is required for postmeiotic anther development in rice. Plant Physiology, 154(1) (2010), 149-162. (*通讯作者).
Gao XC, Liang WQ, Yin CS, Ji SM, Wang HM, Su X, Guo CC, Kong HZ, Xue HW, Zhang DB*. The SEPALLATA-like gene OsMADS34 is required for rice inflorescence and spikelet. Plant Physiology, 153(2) (2010), 728-740. (*通讯作者).
Wang C, Jiang LX, Rao J, Liu YN, Yang LT, Zhang DB*. Evaluation of four genes in rice for their suitability as endogenous reference standards in quantitative PCR. Journal of Agriculture Food Chemistry, 58(22) (2010), 11543-11547. (*通讯作者).
Yuan Z, Gao S, Xue DW, Luo D, Li LT, Ding SY, Yao X, Wilson ZA, Qian Q, and Zhang DB*. RETARDED PALEA1 (REP1) controls palea development and floral zygomorphy in rice. Plant Physiology, 149(1) (2009), 235-244. (*通讯作者).
Zhang DB*, and Wilson ZA. Stamen specification and anther development in rice. Chinese Science Bulletin, 54(14) (2009), 2342-2353. (*通讯作者).
Wilson ZA*, and Zhang DB. From Arabidopsis to rice, pathways in pollen development. Journal of Experimental Botany, 60(5) (2009), 1479-1492. (*通讯作者).
Liu J, Guo JC, Zhang HB, Li N, Yang LT, and Zhang DB*. Development and in-house validation of the event-specific polymerase chain reaction detection methods for genetically modified soybean MON89788 based on the cloned integration flanking sequence. Journal of Agriculture Food Chemistry, 57(22) (2009), 10524-10530. (*通讯作者).
Guo JC, Yang LT, Liu X, Zhang HB, Qian BJ, and Zhang DB*.Applicability of the Chymopapain gene used as endogenous reference gene for transgenic Huanong No,1 papaya detection.Journal of Agriculture Food Chemistry, 57(15) (2009), 6502-6509. (*通讯作者).
Guo JC, Yang LT, Liu X, Guan XY, Jiang LX, and Zhang DB*. Characterization of the exogenous insert and development of event-specific PCR detection methods for genetically modified Huanong No, 1 papaya. Journal of Agriculture Food Chemistry, 57(16) (2009), 7205-7212. (*通讯作者).
Jiang LX, Yang LT, Zhang HB, Guo JC, Marco M, Van den EG, and Zhang DB*. International collaborative study of the endogenous reference gene, Sucrose Phosphate Synthase (SPS), used for qualitative and quantitative analysis of genetically modified rice. Journal of Agriculture Food Chemistry, 57(9) (2009),3525-3532. (*通讯作者).
Yang LT, Guo JC, Zhang HB, Liu J, and Zhang DB*. Qualitative and quantitative event-specific PCR detection methods for oxy-235 canola based on the 3' integration flanking sequence. Journal of Agriculture Food Chemistry, 56(6) (2008),1804-1809. (*通讯作者).
Yang LT, Zhang HB, Guo JC, Pan LW, and Zhang DB*. International collaborative study for the endogenous reference gene, LAT52, used for qualitative and quantitative analysis of genetically modified tomato. Journal of Agriculture Food Chemistry , 56(10) (2008), 3438-3443. (*通讯作者).
Dong W, Yang LT, Shen KL, Kim BH, Kleter GA, Marvin HJP, Guo R, Liang WQ, and Zhang DB*. GMDD, a database of GMO detection methods. BMC Bioinformatics, 9 (2008), 260. (*通讯作者).
Yang LT, Liang WQ, Jiang LX, Li WQ, Cao W, Wilson ZA, and Zhang DB*, A novel universal real-time PCR system using the attached universal duplex probes for quantitative analysis of nucleic acids. BMC Molecular Biology, 9 (2008), 54. (*通讯作者).
Zhang DS, Liang WQ, Yuan Z, Lia N, Shi J, Wang J , Liu YM, Yu WJ, and Zhang DB*. Tapetum Degeneration Retardation is critical for aliphatic metabolism and gene regulation during rice pollen development. Molecular Plant, 1(4) (2008), 599-610. (*通讯作者).
Zhang HB, Yang LT, Guo JC, Jiang LX, and Zhang DB*. Development of one novel multiple-target plasmid for duplex quantitative PCR analysis of roundup ready soybean. Journal of Agriculture Food Chemistry, 56(14) (2008), 5514-5520. (*通讯作者).
Yang LT, Guo JC, Pan AH, Zhang HB, Zhang KW, Wang ZM, and Zhang DB*. Event-specific quantitative detection of nine genetically modified maizes using one novel standard reference molecule. Journal of Agriculture Food Chemistry, 55(1) (2007), 15-24. (*通讯作者).
Shi XZ, Wu AB, Qu GR, Li RX, and Zhang DB*. Development and characterisation of molecularly imprinted polymers based on methacrylic acid for selective recognition of drugs. Biomaterials, 28(25) (2007), 3741-3749. (*通讯作者).
Yang LT, Pan AH, Zhang HB, Guo JC, Yin CS, and Zhang DB*. Event-specific qualitative and quantitative polymerase chain reaction analysis for genetically modified canola T45. Journal of Agriculture Food Chemistry, 54(26) (2006), 9735-9740.
Li N, Zhang DS, Liu HS, Yin CS, Li XX, Liang WQ, Yuan Z, Xu B, Chu HW, Wang J, Wen TQ, Huang H, Luo D, Ma H, and Zhang DB*. The rice Tapetum Degeneration Retardation gene is required for tapetum degradation and anther development. The Plant Cell, 18(11) (2006), 2999-3014. (*通讯作者).
Chu HW, Qian Q, Liang WQ, Yin CS, Tan HX, Yao X, Yuan Z, Yang J, Huang H, Luo D, Ma H, and Zhang DB*. The FLORAL ORGAN NUMBER4 gene encoding a putative ortholog of Arabidopsis CLAVATA3 regulates apical meristem size in rice. Plant Physiology, 142(3) (2006), 1039-1052.
Li XX, Duan XP, Jiang HX, Sun YJ, Tang YP, Yuan Z, Guo JK, Liang WQ, Chen L, Wang J, Ma H, Yin JY, and Zhang DB*. Genome-wide analysis of basic/helix-loop-helix transcription factor family in rice and Arabidopsis. Plant Physiology, 141(4) (2006), 1167-1184. (*通讯作者).
Jiang DH, Yin CS, Yu AP, Zhou XF, Liang WQ, Yuan Z, Xu Y, Yu QB, Wen TQ, and Zhang DB*. Duplication and expression analysis of multicopy miRNA gene family members in Arabidopsis and rice. Cell Research, 16(5) (2006), 507-518. (*通讯作者).
Yang LT, Pan AH, Zhang KW, Guo JC, Yin CS, Chen JX, Huang C, and Zhang DB*. Identification and quantification of three genetically modified insect resistant cotton lines using conventional and TaqMan real-time polymerase chain reaction methods. Journal of Agriculture Food Chemistry, 53(16) (2005), 6222-6229. (*通讯作者).
Yang LT, Xu SC, Pan AH, Yin CS, Zhang KW, Wang ZY, Zhou ZG, and Zhang DB*. Event-specific qualitative and quantitative PCR detection of genetically modified MON863 maize based on the 5’-transgene integration sequence. Journal of Agriculture Food Chemistry, 53(24) (2005), 9312-9318. (*通讯作者).
Yang LT, Pan AH, Jia JW, Ding JY, Chen JX, Huang C, Zhang CM, and Zhang DB*. Validation of a tomato specific gene, LAT52, used as an endogenous reference gene in qualitative and real-time quantitative PCR detection of transgenic tomatoes. Journal of Agriculture Food Chemistry, 53(2) (2005), 183-190. (*通讯作者).
Li H, Xu L, Wang H, Yuan Z, Cao XF, Yang ZN, Zhang DB, Xu Y, and Huang H*, The Putative RNA-dependent RNA polymerase RDR6 acts synergistically with ASYMMETRIC LEAVES1 and 2 to repress BREVIPEDICELLUS and MicroRNA165/166 in Arabidopsis leaf development, The Plant Cell, 17(8) (2005), 2157-2171.
Ding JY, Jia JW, Yang LT, Wen HB, Zhang CM, Liu WX, and Zhang DB*.Validation of a rice specific gene, Sucrose Phosphate Synthase, used as the endogenous reference gene for qualitative and real-time quantitative PCR detection of transgenes. Journal of Agriculture Food Chemistry, 52(11) (2004), 3372-3377. (*通讯作者).
Huang YH, Liang WQ, Pan AH, Zhou ZA,Cheng H, Chen JX, and Zhang DB*. Production of FaeG, the major subunit of K88 fimbriae, in transgenic tobacco plants and its immunogenicity in mice. Infection and Immunity, 71(9) (2003), 5436-5439. (*通讯作者).
Zhang YL, Zhang DB*, Li WQ, Chen JQ, Peng YF, and Cao W. A novel real-time quantitative PCR method using attached universal template probe. Nucleic Acids Research, 31(20) (2003), e123. (*通讯作者).
