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DETERMINATION OF PROTEIN PURITY AND HETEROGENEITY BY CAPILLARY GEL ELECTROPHORESIS AND CAPILLARY ISOELECTRIC FOCUSING |
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Antibodies, protein-based therapeutics, and other recombinant proteins are final products in biotechnological and pharmaceutical industry. Determination of their purity, stability, and heterogeneity is of utmost importance since post-translational modifications as well as degradation processes can change drastically the biological activity of these proteins.