【技术特点】-- 法庭科学DNA研究方案

法庭科学DNA研究方案

阅微基因拥有一代测序、二代测序、qPCR 及基因芯片等平台，可以多方位对人源细胞、微生物等的STR、SNP、DNA 甲基化、Mt-DNA 进行单一 / 集成化的长度多态性或序列多态性等方面检测，获取从简单到复杂的遗传信息，为法医的研究提供更多的解决方案及简易的工作流程。

重要合作成果

1. IF: 6.513  相关产品：Microreader™ 21 (Direct) ID System

Investigation of cross-contamination among human cell lines used in China. International journal of cancer, 2017. 

2. IF: 5.637  相关产品：Microreader™ 23sp ID System 

Analysis of genetic polymorphisms and mutations at 23 autosomal STR loci in Guangdong Han population. Forensic Science International: Genetics, 2019. 

3. IF: 5.637  相关产品：Microreader™ 23sp ID System 

Validation of the Microreader™ 23sp ID system: A new STR 23-plex system for forensic application.  Forensic Science International: Genetics, 2017. 

4. IF:5.637  相关产品：Microreader™ 23sp ID System 

Multistep microsatellite mutation at D18S51 locus in a parentage testing case. Forensic Science International: Genetics Supplement Series, 2017. 

5. IF: 5.637  相关产品：Microreader™ 23sp ID System 

Genetic polymorphism of 22 autosomal STR markers in a Han population of Southern China.  Forensic Science International: Genetics, 2016.  

6. IF: 5.637  相关产品：Microreader™ 23sp ID System 

Genetic polymorphisms of 22 autosomal STR loci in Chinese Han population.  Forensic Science International: Genetics Supplement Series, 2015. 

7. IF: 5.206  相关产品：Microreader™ 20A ID System

Thalassaemia intermedia caused by coinheritance of a β‐thalassaemia mutation and a de novo duplication of α‐globin genes in the paternal allele. BRIT J HAEMATOL, 2019. 

8. IF: 4.884  相关产品：Microreader™ 21 (Direct) ID System

Developmental Validation of Y-SNP Pedigree Tagging System: a panel via quick ARMS PCR. FORENSIC SCI INT-GEN, 2020.

9. IF: 3.439  相关产品：Microreader™ 21 (Direct) ID System

Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas. CANCER CELL INT, 2020.

10. IF: 2.569  相关产品：Microreader™ 20A ID System

Developmental validation of the MicroreaderTM 20A ID system. Electrophoresis, 2019. 

11. IF: 2.4 

Development one novel multiplex PCR system for forensic individual identification using insertion/deletion polymorphisms. ELECTROPHORESIS, 2019.

12. IF: 2.094  相关产品：Microreader™ 19X ID System

Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown. INT J LEGAL MED, 2020.

13. IF: 2.094  相关产品：Microreader™ 24Y ID System

Developmental validation study of a 24-plex Y-STR direct amplification system for forensic application. INT J LEGAL MED, 2019.

14. IF: 1.99  相关产品：Microreader™ 21 (Direct) ID System

Genetic and chromosomal variation-caused inconsistencies in two parental tests. FORENSIC SCI INT, 2019.

15. IF: 1.276  相关产品：Microreader™ 19X ID System

Loss of heterozygosity detected at three short tandem repeat locus commonly used for human DNA identification in a case of paternity testing. Legal Medicine, 2017. 

阅微基因拥有一代测序、二代测序、qPCR 及基因芯片等平台，可以多方位对人源细胞、微生物等的STR、SNP、DNA 甲基化、Mt-DNA 进行单一 / 集成化的长度多态性或序列多态性等方面检测，获取从简单到复杂的遗传信息，为法医的研究提供更多的解决方案及简易的工作流程。

重要合作成果

1. Genetic distribution of 39 STR loci in 1027 unrelated Han individuals from Northern China. FSI: Genetics（影响因子：5.637）

2. Concurrent copy number variations on chromosome 8 and 22 combined with mutation at FGA locus revealed in a parentage testing case.FSI: Genetics（影响因子：5.637）

3. Genetic polymorphism of 22 autosomal STR markers in a Han population of Southern China. FSI: Genetics（影响因子：5.637）

4. Validation of the Microreader 23sp ID system: A new STR 23-plex system for forensic application. FSI: Genetics（影响因子：5.637）

5.A genomic audit of newly-adopted autosomal STRs for forensic identification. FSI: Genetics（影响因子：5.637）

6. Development of a rapid 21‐plex autosomal STR typing system for forensic applications. Electrophoresis(影响因子：2.569)

7. Inconsistent genotyping call at DYS389 locus and implications for interpretation. International Journal of Legal Medicine(影响因子：2.316)

8. Population data for 22 autosomal STR loci in the Uygur ethnic minority. International Journal of Legal Medicine(影响因子：2.316)

9. Forensic molecular genetic diversity analysis of Chinese Hui ethnic group based on a novel STR panel. International Journal of Legal Medicine(影响因子：2.316)

【技术特点对用户带来的好处】-- 法庭科学DNA研究方案

【典型应用举例】-- 法庭科学DNA研究方案