The Mycobacterium tuberculosis Phagosome
Tuberculosis is currently the most devastating human bacterial disease, causing millions of deaths annually and infecting an overwhelming percentage of the global population. Its success as a scourge lies in the ability of Mycobacterium tuberculosis to prevent normal phagolysosome biogenesis, essential to the destruction of invading microorganisms, inside macrophages. Recent work has identified host GTPases involved in the block of normal phagolysosome biogenesis during mycobacterial infection and has provided a set of methods, in particular efficient macrophage transfection, which will prove essential in examining the role of host effectors in this process.
- Structural Studies of Proteins in Solution Using Proton Nuclear Magnetic Resonance
- Subtelomeric and/or Subcentromeric Probe Sets
- Microarray Approaches for Analysis of Cell Cycle Regulatory Genes
- Flow Cell Assays with Microtubules: Motility/Dynamics in Fluorescence and VE-DIC
- Cytometric Detection and Quantitation of Cell-Cell Electrofusion Products
- On-Line Concentration of Environmental Pollutant Samples by Using Capillary Electrophoresis
- Adult Stem Cells for the Treatment of Neurological Disease
- Tools for Predicting Binding and Insertion of CPPs into Lipid Bilayers
- Retroviral Vector-Based Approaches for the Generation of Human Induced Pluripotent Stem Cells from Fibroblasts and Keratinocytes
- 40种常用细胞培养基配方