Antibody Techniques Used in the Study of Anaplastic Lymphoma Kinase-Positive ALCL
Antibodies enable relatively simple, rapid, and reproducible studies to be performed on protein expression in both normal and neoplastic cells. The availability of suitable reagents for routine diagnostic use has revolutionized the study of leukemia and lymphoma pathology. The use of antibodies specific for anaplastic lymphoma kinase (ALK) protein has permitted the identification of the tumor entity ALK-positive from the poorly defined morphological category of anaplastic large cell lymphoma. Antibody techniques have also provided major new insights into the biology of these tumors. This chapter describes the use of antibodies in both immunolabeling (immunocytochemical and immunofluorescence) procedures and in biochemical procedures in the study of ALK-positive ALCL.
- Analysis of Telomerase Activity and Telomere Function in Cancer
- Determination of Cyclin D1 Expression by Quantitative Real-Time, Reverse-Transcriptase Polymerase Chain Reaction
- Targeted Chemotherapy in Drug-Resistant Tumors, Noninvasive Imaging of P-Glycoprotein-Mediated Functional Transport in Cancer, a
- An Overview of Chemosensitivity Testing
- Electroporative Gene Transfer
- Genetic Epidemiology Studies in Hereditary Non-Polyposis Colorectal Cancer
- THP1核酸代谢
- Microdissection of Histologic Sections: Manual and Laser Capture Microdissection Techniques
- 跨越世纪的生命赞歌(第二部分)
- 走进自噬,研究自噬