双链断裂重组模型(model of double-strand breaks recombination)
关键词: 双链断裂 重组模型来源: 互联网
该模型认为:一条染色体的两条链都发生了断裂,断裂是由内切酶水解磷酸二脂键的结果。DNA断裂之后由核酸外切酶扩大缺口。接着是断裂链的游离3’端插入到具有完整双链的同源染色体中,形成D-环结构。在DNA聚合酶的作用下,断裂两条链分别以完整链为模板开始合成。最后再通过断裂重接过程完成重组。
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