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Mycoplasma and Ureaplasma Infections

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Organisms of the class Mollicutes (meaning soft-skin) have regressively evolved, by genome reduction, from Gram-positive bacterial ancestors, namely certain clostria (1 ). The taxonomy of the class Mollicutes, containing four orders, five familes, and eight genera, is shown in Table 1 (2 ) The term “mollicute” is sometimes trivially used to describe any organism in the class. The term “mycoplasma” might be used best to describe any member of the genus Mycoplasma , but is also used, as in this chapter, in a trivial way to refer to any organism in the class. Table 1  Taxonomy and Properties of Mycoplasmas (class Mollicutes; Adapted from ref. 2 )

Classification

Current no. of Recognized species

Genome size(kbp)

Mel%G+C content

Distinctive properties

Habitat

Order I: Mycoplasmatales Family I:Mycoplasmataceae Genus I:Mycoplasma

100

580-l300

23-41

Optimum growth at 37�C

Humans,animals,plants,insects

Genus II Ureaplasma

6

730-1160

27-30

Urease positive

Humans,animals

Order II Entomoplasmatales

         

Family I Entomoplasmataceae

         

Genus I Entomoplasma

5

790-l140

27-29

Optimum growth

Plants,insects

       

at 30�C

 

Genus II Mesoplasma

12

870-1100

27-30

 

Plants,insects

Family II Spiroplasmataceae

         

Genus I:Spiroplasma

17

940-2240

25-31

Helical filaments

Arthropods(includ-

         

ing insects), plants

Order III Acholeplasmatales

         

Family I Acholeplasmataceae

         

Genus I Acholeplasma

13

About 1600

27-36

 

Animals,plants,

         

insects

Order IV Anaeroplasmatales

         

Family I Anaeroplasmataceae

         

Genus I.Anaeroplasma

4

About 1600

29-33

Oxygen-sensitive

Bovine-ovine rumen

       

obligate anaerobes

 

Genus II Asteroleplasma

1

About 1600

40

Oxygen-sensitrve

Bovine-ovine rumen

       

obligate anaerobes

 

Uncultivated,unclassified MLOs

 

506-1185

23-29

Uncultivated as yet

Plants,insects

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