R Statistical Tools for Gene Discovery
关键词: statistical tools gene来源: 互联网
A wide assortment of R tools are available for exploratory data analysis in high-dimensional settings and are easily applicable to data arising from population-based genetic association studies. In this chapter we illustrate the application of three such approaches, namely conditional inference trees, random forests, and logic regression. Through applications to simulated data, we explore the relative utility of each approach for uncovering underlying association between genetic polymorphisms and a quantitative trait.
推荐方法
- Sedimentation Velocity Ultracentrifugation Analysis for Hydrodynamic Characterization of G-Quadruplex Structures
- Using Arabidopsis-Related Model Species (ARMS): Growth, Genetic Transformation, and Comparative Genomics
- Analysis of Gene-Specific DNA Methylation Patterns by Pyrosequencing Technology
- High-Throughput Expression in Microplate Format in Saccharomyces cerevisiae
- Rat Models of Cardiovascular Diseases
- Isolation and Analysis of DNA Derived from Nucleosome-Free Regions
- Electrophoretic Mobility Shift Assays for the Analysis of DNAProtein Interactions
- Cryopreservation
- In Situ Nick Translation at the Electron Microscopic Level
- Rapid Preparation of RNA Samples Using DNA-Affinity Chromatography and DNAzyme Methods