实验方法>
遗传学实验技术>
基因表达差异显示实验>Functional Mapping of Developmental Processes: Theory, Applications, and Prospects
Functional Mapping of Developmental Processes: Theory, Applications, and Prospects
关键词: functional mapping developmental来源: 互联网
Functional mapping is a statistical tool for mapping quantitative trait loci (QTLs) that control the developmental pattern and process of a complex trait. Functional mapping has two significant advantages beyond traditional QTL mapping approaches. First, it integrates biological principles of trait formation into the model, enabling the biological interpretation of QTLs detected. Second, functional mapping is based on parsimonious modeling of mean-covariance structures, which enhances the statistical power of QTL detection. Here, we review the basic theory of functional mapping and describe one of its applications to plant genetics. We pinpoint several areas in which functional mapping can be integrated with systems biology to further our understanding of the genetic and genetic regulatory underpinnings of development.
推荐方法
- Capillary Electrophoresis of an X-Chromosome STR Decaplex for Kinship Deficiency Cases
- Methylation-Specific PCR In Situ Hybridization
- Detection of Copy Number Changes at Multiple Loci in DNA Prepared from Formalin-Fixed, Paraffin-Embedded Tissue by Multiplex Lig
- Methods for Selecting Effective siRNA Sequences by using Statistical and Clustering Techniques
- Constitutive Expression Vectors: PGK
- The Use of Double-Stranded RNA to Knock Down Specific Gene Activity
- FIV Vectors
- Generation of Chimeras by Microinjection
- Introduction to DNA Sequencing
- Overview of Whole-Genome Essentiality Analysis