The Use of Flow Cytometry and RT-PCR in the Detection of Circulating PSA-Positive Cells in Prostate Cancer
Prostate cancer is the most common malignancy diagnosed in men in the Western hemisphere. Once early tumors are detected, prognosis is largely unpredictable, and clinicians are currently unable to inform the patient whether his tumour is likely to progress. New criteria to define the aggressive and metastatic potential of prostate cancer are needed, particularly in view of the recent controversies and evidence from North American studies questioning the benefits of radical surgery over observation in early-stage prostatic adenocarci-noma (1 -3 ). Furthermore, even in patients where the disease appears to be confined to the prostate, cancers can be understaged in over 50% of cases, with resulting positive surgical margins, extracapsular extension, and potential treatment failure (4 ).
- 测定遗传变异在多发性硬化症中所发挥作用的程度
- Progress in siRNA Delivery Using Multifunctional Nanoparticles
- Lentiviral Vectors
- Proteome Studies of Filamentous Fungi
- Rat Strain Repositories
- Cell Microarray for Functional Exploration of Genomes
- Quantitative Analysis of SNPs in Pooled DNA Samples by Solid-Phase Minisequencing
- Characterization of Enzymes That Initiate Base Excision Repair at Abasic Sites
- Production of Transgenic Sheep
- Design, Synthesis, and Screening of Biomimetic Ligands for Affinity Chromatography