Random Mutagenesis for Protein Breeding
Mutagenesis is an essential process in evolution, generating an array of genetically unique organisms from which natural selection selects the best-suited to the immediate environment. Compatible and favorable mutations quickly converge; because offspring may inherit distinct advantageous mutations from both parents, and thus dramatically increase their survival rate. Parental crossing results in the accumulation of advantageous mutations in offspring. Evolutionary adaptation has allowed organisms to progressively specialize, and colonize, even in the most extreme of habitats.
- Microscale Thermophoresis as a Sensitive Method to Quantify Protein: Nucleic Acid Interactions in Solution
- Comparative Genomics-Based Prediction of Protein Function
- Intracellular pH Measurements In Vivo Using Green Fluorescent Protein Variants
- Rat Spermatogonial Stem Cell-Mediated Gene Transfer
- Genetic Modification of the Mouse: General Technology Pronuclear and Blastocyst Injection
- Isolation and Analysis of DNA Derived from Nucleosome-Free Regions
- Mouse Surgical Models in Cardiovascular Research
- Proteomics-Based Method for Risk Assessment of Peroxisome Proliferating Pollutants in the Marine Environment
- Reporter Cell Lines for the Detection of Herpes Simplex Viruses
- Using Recombineering to Generate Point Mutations:galK-Based PositiveNegative Selection Method