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基因表达差异显示实验>Prenatal Detection of Chromosome Aneuploidy by Quantitative-Fluorescence PCR
Prenatal Detection of Chromosome Aneuploidy by Quantitative-Fluorescence PCR
关键词: prenatal detection chromosome来源: 互联网
QF-PCR refers to the amplification of chromosome-specific polymorphic microsatellite markers using fluorescence-labelled primers, followed by semi-quantitative analysis of the products on a genetic analyser to determine copy number and/or imbalances of specific chromosomal material. This approach is now widely used for rapid prenatal diagnosis of the common trisomies. In addition, it can successfully detect maternal cell contamination and mosaicism in prenatal material.
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