Trophic Influences on Neural Tissue Transplants: Delivery Methods and Co-graft Interaction
As described in several different chapters of this book, neural transplantation has been used extensively during the past two decades as a model for neural development and maturation, as well as a screening tool for different factors that might affect these processes. In addition, neural transplantation of fetal neurons is considered a plausible avenue for treatment of different neural degenerative diseases, such as Parkinson’s disease (PD) (for review, see Hoffer et al., 1988 ; Bakay and Herring, 1989 ; Granholm et al., 1989 ; Lindvall et al., 1990 ; Hitchcock, 1995 ; Kordower et al., 1995 ). PD has served as the prototype for study of transplantation in neurodegenerative disease, perhaps because, in patients with PD, a set of conspicuous symptoms is caused by loss of neurons in a single nucleus, the substantia nigra pars compacta (Shults, 1992 ).
- Peptide Bioinformatics- Peptide Classification Using Peptide Machines
- Toxin-Induced Death of Neurotrophin-Sensitive Neurons
- Automated Conditioning in Larval Zebrafish
- Cerebral Angiogenesis: A Realistic Therapy for Ischemic Disease
- Expression of m-Calpain in Escherichia coli
- Isolation and Properties of an In Vitro Human Outer Blood-Retinal Barrier Model
- Intraparenchymal Delivery and Its Discontents
- Synthesis of Cell-Penetrating Peptides and Their Application in Neurobiology
- fMRI of Language Systems
- Isolation and Characterization of Synaptic and Nonsynaptic Mitochondria from Mammalian Brain