Thymus Organogenesis and Development of the Thymic Stroma
T-cell development occurs principally in the thymus. Here, immature progenitor cells are guided through the differentiation and selection steps required to generate a complex T-cell repertoire that is both self-tolerant and has propensity to bind self major histocompatibility complex. These processes depend on an array of functionally distinct epithelial cell types within the thymic stroma, which have a common developmental origin in the pharyngeal endoderm. Here, we describe the structural and phenotypic attributes of the thymic stroma, and review current cellular and molecular understanding of thymus organogenesis.
- GAPDH抗体|GAPDH抗体大全-艾美捷指导您购买合适的GAPDH抗体
- 人sCD40配体(sCD40 Ligand)ELISA试剂盒 说明书
- 人可溶性CD14(sCD14)ELISA试剂盒 说明书
- 山羊关节炎(arthritis)酶联免疫分析(ELISA)
- ELISA标准操作及技术服务的常见问题分析
- 制备单克隆抗体骨髓瘤细胞与脾细胞的融合
- Synthesis of Antimicrobial Peptides Using the SPOT Technique
- Real-Time PCR Methods to Study Expression of Genes Related to Hypermutability
- Production of Monoclonal Antibodies for the Detection of Chemically Modified DNA
- Direct Immunofluorescence Labeling