实验方法> 免疫学技术> 抗体抗原实验>Studying NK Cell/Dendritic Cell Interactions

Studying NK Cell/Dendritic Cell Interactions

关键词: studying nk cell dendritic cell interactions来源: 互联网

Although NK cells were originally identified as “naturally” active cells believed to follow a cell-autonomous activation program, it is now widely accepted that NK cells need to interact with dendritic cells for their full functional activation and for their homeostasis. In this chapter, we will provide an experimental guide to the analysis of NK cell/DC interactions in vitro and in vivo. We have put special emphasis on the recently developed mouse models allowing the inducible and specific ablation of various subsets of DCs and other myeloid cells.

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