Recombinant Fusion Toxins Directed Against the Human Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Receptor
Acute myeloid leukemia (AML) has an annual incidence of 2.4 cases per 100,000 persons and is the most common form of acute leukemia in adults (1 , 2 ). AML is a model for drug-resistant human cancers, and current therapies for AML possess a narrow therapeutic margin. The use of high-dose and intensive chemotherapy regimens produces remission in the majority of patients with AML; however, most cases subsequently relapse and eventually succumb to chemotherapy-refractory disease (3 , 4 ). Attempts to further increase chemotherapy dose intensity in AML treatment regimens often result in an increased incidence of therapy-related morbidity and mortality.
- CTL杀伤靶细胞诱导细胞凋亡
- G蛋白结合受体介导的信号途径
- PCR-SSO预杂交和杂交
- 玻片凝集反应
- 单克隆抗体技术:动物的选择与免疫
- 细菌的生理、生化试验简介
- Production and Characterization of T Cell Hybridomas
- Isolation and Generation of Clinical-Grade Dendritic Cells Using the CliniMACS System
- Inherited Complement Deficiencies in Animals
- Detection of Immunoglobulin Gene Rearrangements