实验方法> 免疫学技术> 抗体抗原实验>Purification of C1q Receptors and Functional Analysis

Purification of C1q Receptors and Functional Analysis

关键词: purification c1q receptors functional analysis来源: 互联网

The recognition subunit of C1, C1q, has emerged as an important player in various pathophysiologic conditions largely in part due to its ability to interact with pathogen-associated or cell surface expressed ligands and receptors. Identification and purification of these molecules is therefore of paramount importance if we are to procure valuable information with regards to the structure, function, and cell surface distribution. Since the interaction of C1q is better served when the receptors are purified from homologous species, we discuss here a simple guideline for the purification and characterization of the two C1q receptors, cC1qR (calreticulin) and gC1qR, from human cell lines.

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